After 4th round of LU-177, Started on Cabazitaxel. Advice please

[bellyhappy]

Did my 4th round of LU-177. PSA dropped marginally for two months. Scan started to show very little improvement and some of the previous lesions have become active again. Oncologist suggested Cabazitaxel. Just started yesterday.

Any advice on the side effects and what to do during the Cabazitaxel treatment? What is the next possible treatment available? Did a genetic test, but nothing from that area indicated any other possible genes. Thanks

[tango65]

Some info about chemo by an expert in the treatment of PC:

grandroundsinurology.com/dr...

[EdBacon]

Many people find the side effects of Cabazitaxel to be minimal. That's been the case for me. It's been fairly easy for me so far. The second and third days have been the most difficult, but comparable to having a cold. I have slept quite a bit more in the first week, but after that it's pretty much back to normal.

I get my third infusion on Monday. Cabazitaxel can be an effective chemotherapy. It reduced my pain from intolerable levels down to nothing in a matter of days after the first infusion. I have some pain on and off since then, but overall much better since I started. It's definitely worth a shot as far as I'm concerned.

[Parscore in reply to EdBacon]

Have you had any hair loss from the noggin. I have a good crop going at age of 72 and I would hate to say good-by

[EdBacon in reply to Parscore]

There's no hair loss with Cabazitaxel.

[Parscore in reply to EdBacon]

Good to know thanks

[Pwjpp55]

Did you stop Lu177? Or will you continue it with Cabazataxel? What was your preLu177 starting and last PSA? Finally, did you tolerate the Lu177 ok?

[bellyhappy in reply to Pwjpp55]

After the 4th LU-177, the PSA improved marginally...and then two months later , it shot up from 6 to 39. Therefore, now starting on Cabazitaxel....LU -177 treatment is fine. Major side effects esp after the 4th are fatigue, very dry mouth ( saliva excretion is impacted). Hope this help.

[Pwjpp55 in reply to bellyhappy]

Yes, thanks. Good luck on the Cabazataxel.

[meowlicious99 in reply to bellyhappy]

I am sorry you haven't had more luck with LU . Hope Cabazi comes through for you!!