Time between Pluvicto infusions

[venecia1983]

How often should you have Pluvicto infusions? Every 4 or 6 weeks? Some of my appointments are scheduled less than 5 weeks apart and that concerns me. Any feedback is appreciated. Thanks

[Tall_Allen]

If your blood work is good, why not?

[venecia1983 in reply to Tall_Allen]

Good point. Thanks

[tango65]

It is variable. When a I had the treatment in Germany in 2016, they told me 4 to 6 weeks, 4 weeks minimum interval.

[Fightinghard]

as part of a clinical trial, they have the LU injections for me scheduled every 8 weeks.

[Seasid in reply to Fightinghard]

Can you please fill out your profile information?

[Seasid]

How many Pluvicto infusions do you plan to have?

[Fightinghard in reply to Seasid]

4 injections. SPLASH trial

[Seasid in reply to Fightinghard]

this is your clinical trial:

clinicaltrials.gov/ct2/show...

[venecia1983]

Still not sure. I guess it depends on the result, but the insurance has approved 6. The time between the 1st and 2nd one is 35 days and between 3rd and 4th is 36 days.

[Seasid in reply to venecia1983]

And what is a time between a second and the third infusion?

Will you get GA68 PSMA PET scans after each of infusions? How will they know when to stop?

Which organisation is giving you the infusions?

Again, you can get only 6 Lutetium infusions in your lifetime. It is no point to go forward with the next infusion if they stop working.

What is the dose you will receive each time? How did they decide about the dose?

[Fightinghard in reply to Seasid]

bone and psma pet cat scans every 8 weeks. Day prior to injection. 7.8mg I think each dose

[Seasid in reply to Fightinghard]

this is your clinical trial:

clinicaltrials.gov/ct2/show...

Could you please fill out your profile information?

[Seasid]

i believe you can get only 6 in your lifetime.

[Fight11]

My husband has them every 6 weeks and will be having 6 infusions!!

[Muffin2019 in reply to Fight11]

hiw is he handling the eide effects and what side effects dies he have ?

[Fight11 in reply to Muffin2019]

GI upset and some diarrhea

[Muffin2019 in reply to Fight11]

did they give him medicine to help with that ?

[Fight11 in reply to Muffin2019]

No. I gave him some gas x and pepto bismol

[nobaday]

For people in Russia and Turkey I have seen TWO WEEK intervals. As long as blood work good.

But protocol from FDA approval from VISION trial requires I believe 6 week intervals.

Thats the FANTASTIC thing about Lu177. Targeted with minimal side affects. You can go out for dinner and a beer/ afterwards…. Just stay away from small children, small dogs and pregnant women!!!! And airport radiation devices!!

[ishitasen]

No this should not be a concern to you. Depending upon your performance status and bone marrow reserves the interval between the two therapy can be shortened.

[ishitasen]

No this should not be a concern to you. Depending upon your performance status and bone marrow reserves the interval between the two therapy can be shortened.

[venecia1983 in reply to ishitasen]

Thank you!