Multiple (7) nonenlarged but PSMA avid retroperitoneal and left common iliac lymph nodes. Thesedemonstrate variable PSMA avidity from SUV max of 2 and the upper abdomen (image 196) to 8.8 and theleft common iliac region (image 266). The most PSMA avid lymph node in the left common iliac lymphnodes measures 4 mm in short axis with an SUV max of 8.8 (image 266). This is consistent withintermediate miPSMA expression.
No bone or organ mets.
Dr suggested LU-177 as my next treatment and started the insurance approval process.
My complete treatment history is in my profile under my story. I was wondering if anyone else had a similar history and what side effects I should expect from LU-177. In addition, I would appreciate any other suggestions from this community.
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venecia1983
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With lymph nodes metastases only, the side effects will be minimal and transient. I was in a similar situation 6 years ago and I had only fatigue and transient edema.
The mets were gone after one treatment with Lu 177 PSMA. I continued treatment with ADT and in 2020 I added darolutamide. Two metastases appeared in retroperitoneal nodes in June 2022, six years after the Lu 177 PSMA treatment. These metastases are in different lymph nodes than in 2016, The mets of 2016 continue to be PSMA and FDG negative.
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