Dendritic Cell Therapy : Provenge... - Advanced Prostate...

Advanced Prostate Cancer

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Dendritic Cell Therapy

TEBozo profile image
9 Replies

Provenge seems to be the FDA approved vaccine but , I believe Medicare won't pay for it unless you have become castrate resistant. Out of pocket,I understand it costs around 150,000. My belief is why damage my immune system with maximum ADT and THEN try to build it up again. Why not take a relatively healthy immune system and make it even stronger? I am on my second of three therapy sessions. The first resulted in an immediate clearing of my sinuses then a fever about 24 hours later of 99.5 that broke after about 6 hours. I may or may not have the same immune response from this session. One more next week and they provide take home shots that you administer in the fat of your stomach.

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TEBozo profile image
TEBozo
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Tall_Allen profile image
Tall_Allen

What makes you think that ADT damages the immune system? All the evidence points in the opposite direction.

We have a lot to learn about Provenge timing and combinations. You may be interested in the section on early use of immunotherapy in the article below:

prostatecancer.news/2019/02...

tango65 profile image
tango65

I wonder how you know their vaccine is effective against PC. How do you know your immune system is being made stronger?

A search in PUBMED does not show any study published by Drs Robinson and Hossami about vaccines or prostate cancer.

I have been in immunological vaccine trials, but the vaccine was made at NIH and there were preliminary studies published.

TEBozo profile image
TEBozo in reply totango65

Did you do well with therapy? Was it Provenge?

tango65 profile image
tango65 in reply toTEBozo

I did well. It was a different vaccine with a modified vaccinia virus.

TEBozo profile image
TEBozo in reply totango65

I'm not sure what your therapy really means but this is from Veritas' website.

Dendritic cells act as the liaison between your different immune systems. They help the body to notice and recognise antigens which it needs to fight. In the case of cancer treatment, they teach your immune system to identify cancer cells, also called tumour antigens. This means that your adaptive immune system recognises cancer cells and can jump in faster to produce more of the cells which fight cancer. Unfortunately, Dendritic Cells are seldom active in adequate numbers.

keepinon profile image
keepinon

I hope you keep us up to date on how your therapy goes. Good luck!!

TEBozo profile image
TEBozo in reply tokeepinon

Thanks. Second therapy session today. Not much reaction except to the anti inflammatory injection which made me red. My PSA has risen from 0.19 to 0.55 over, say, 8 months then after 20# weight loss and mostly vegetables and consistently taking a specific supplement (expensive) regimen, it dropped to 0.51. My goals and reason for the Dendritic Cell Therapy is to have the longest progression free survival time as possible. Because of my PSA drop, my RO was not recommending a Gallium PSMA scan and only a PSA in November/December. I'll do it each month and keep on keeping on.

keepinon profile image
keepinon

Dendritic Cancer Cell Therapy? Different from Provenge? Do you mind sharing the cost in Tijuana? Curious about your expensive supplement regimen. Is it a few or a whole bunch of different supplements?

TEBozo profile image
TEBozo in reply tokeepinon

$16, 750 plus my travel. I'll post my supplement regime later.

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