Chemotherapy may reset hormone sensitivity

[Doggedness]

Hello everyone,

I am looking for an article that I am sure I read somewhere, which found that chemotherapy given to hormone castrate patients, in some cases, reset the hormone-sensitivity clock, meaning that for some time the patients were once again able to respond to ADT. Does anyone here remember it? Or better still, does anyone recall who was involved in the study? I have Googled all sorts of combinations to no success.

[j-o-h-n]

Good idea to Update:

Would you please be kind enough to tell us your bio. Age? Location? When Treatment(s)? Treatment center(s)? Scores Psa/Gleason? Medications? Doctor's name(s)?

ALL INFO IS VOLUNTARY, but it helps us help you and helps us too. When you respond, you might want to copy and paste it in your home page for your use and for other members’ reference.

Note: Answers are for your benefit, not mine.

THANK YOU AND KEEP POSTING!!!

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 06/03/2022 10:47 PM DST

[Doggedness in reply to j-o-h-n]

my husband is the one with pc, diagnosed (after he noticed that his urination was less ‘powerful’) in May2019, Gleason 10, with 8 mets from his skull down to his pelvis. He went on ADT plus Abiraterone (& prednisone). The scan at the one year mark showed normalisation of all mets so we are continuing with his regime. We are also eating less meat and more leafy greens, etc. He was amazingly good at maintaining ‘targeted exercise’ until the gym closed down with Covid (later in Australia than the rest of the world), but still cycles, plays golf and gardens now. He finds it hard to push through the fatigue, but other than that (& the occasional mood plunge) he is doing really well.