Has anyone used DHEA to increase their free testosterone? It is a precursor to testosterone (DHEA->androstenedione->testosterone).
Effect of acute DHEA administration on free testosterone in middle-aged and young men following high-intensity interval training - PubMed
Yes, I did and it caused my PSA to rise substantially and a Choline PET scan afterwards showed increased uptake in a number of places. Obviously, I would not recommend it.
Thanks. Were you doing high testosterone or bipolar androgen therapy?
High testosterone increases PSA and if that is all that you did I don't think it will work for most men.
No, I wasn't taking testosterone at all, and thought this might be a work around. I saw somebody on here propose about exactly what you have proposed and so I tried it. Pregnanalone and DHEA. I was rocking along with a PSA in the 2s after Tulsa Pro, a 90% reduction but still not low enough, but I thought I could try this to increase my T since I have traditionally had lowish T, around 300, and PSA jumped immediately to 6.9, along with as I said, increased uptake in lymph nodes and an indeterminant spot on my scapula. Variables are infinite, no one can say what causes what exactly, but I'm just telling you my experience. I've done radiation and ADT since that time. Seems to be working but as my T rises I guess I'll find out.
Thanks. I'll look for their post.
What I would potentially do is add it to a bipolar androgen therapy program. The therapy takes testosterone very high (DSBs?) and then to sub 20 levels. When T is high my PSA goes to 0.3. When T goes low my PSA gradually goes to zero. My MO and I are working on this program. If I find out something positive about DHEA I intend to discuss it with her.
If you want to increase testosterone to normal levels, have you discussed TRT with your MO? I don't know the logic behind letting T recover. For me it took weeks (after 2 years of 400 mg/wk cypionate injections) but for some guys, it apparently takes months or even years. Is the therapeutic advantage QoL and muscle recovery?
I’m considering it now that my PSAs are <.1 on the Mayo tests for 8 months and .03 in February, <.02 in March, and <.02 in April on a Beckman Coulter dx PSA test I took on my own. Which appears to be my nadir and is the lowest that can be registered on that test. Its an UltaLab test. But Mayo won’t do it so I’d have to go to someone else. Some say wait awhile. I would like to see what my T would go up to on its own but likely not over 300 or so. Quite frankly, I’m ok with that number but I used to take Androgel and I miss those 700 T days. And of course, PSA is the crucial number; it can go up, and then a whole different set of problems arises
The happiest days of my life were when I was going 400 mg cypionate shots. My tT was 2500-4000+. Alas, it only lasted two years. PSA stayed undetectable for a year and then started going up. It went up to 0.17 and I felt that I needed to bail.
Kind of a good thing in a way. I was starting to worry about what the high testosterone would do to me long-term.
TSH, T3, and T4 would help monitor?
Thanks. I'll talk to my NMD. DHEA has a sub-hour half-life. DHEAS half-life is less than a day. So they are attractive, but not attractive enough to risk my thyroid.
I did it unintentionally. I had been taking DHEA for years but after I started ADT it (probably) caused my testosterone to go to 70 so I stopped taking it. Next test, testosterone was more like 15.
Makes sense. How much DHEA did you take? Bypasses the GnRH drugs (ADT).
I think it was 50
Dhea or was that a typo for "Head" - better to give head than taking it...
Good Luck, Good Health and Good Humor.
j-o-h-n Friday 04/15/2022 6:52 PM DST - Uncle Sam's original Birthday
Let's see if I got this. A head being that thing on the top of our body with a face on it.Its better to give someone one of those than to take one of those away?
That's it. I think. As you would probably tell me I am smarter than I think I am.
You hit the nail on the HEAD.........."you're smarter than I think you am"...
Good Luck, Good Health and Good Humor.
j-o-h-n Friday 04/15/2022 7:16 PM DST - Uncle Sam's original Birthday
That's what I keep telling my wife. Me, being the nice husband that I am, let her give me as much head as she wants. Unfortunately that's zero.
Try real jewelry that usually works............
Good Luck, Good Health and Good Humor.
j-o-h-n Friday 04/15/2022 10:33 PM DST - Uncle Sam's original Birthday
I tried real Cracker Jack jewelry. She nibbled. I imagine that is what a minnow would feel like.
You reap what you sow....
Good Luck, Good Health and Good Humor.
j-o-h-n Friday 04/15/2022 10:43 PM DST - Uncle Sam's original Birthday
Is there seasonality to testosterone levels?
Does PSADT calculation make sense when testosterone is increasing 
Do not understand testosterone shbg,free/weakly bound & total
Slight Testosterone Increase While on Lupron/Zytiga
Testosterone and Lupron
