Stopping Zoladex or Lupron

[Arcticfox44]

At what point, if ever, would it be advisable to stop injections of Zoladex or Lupron when they cease to be effective in suppressing PC? I am still on Zoladex shots every 12 weeks, despite its failure to work anywhere near as well as it did initially. Given the known downsides to the shots, I wonder about the reasoning behind the decision to keep going.

[Tall_Allen]

You NEVER stop. One of the reasons for "castration resistance" is that the androgen receptor (AR) becomes overexpressed on the cancer cell. Because of this it becomes more sensitive than ever to even the slightest bit of testosterone. Stopping Zoladex or Lupron at such a stage would cause the cancer cells to replicate like crazy.

[Arcticfox44 in reply to Tall_Allen]

Thanks.

[Magnus1964]

You might add zytiga to the zoladex.

[j-o-h-n]

T_A said don't stop..... so don't stop....... and remember Foxx Pca....

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 02/21/2022 8:01 PM EST

[Spyder54]

C this posted by GP24 earlier if you can get into an LU-177 Trial: eurekalert.org/news-release... give up- Never give in” . Small steps lead to extension of life. Cure will come in some yet to be determined combination. Dr Thomas Setfried of Boston Univ claims to have stopped the Metastisis process in his labs, pointing out he has Not cured cancer, but has stopped the Metastasis process which is what kills us. He should win a Nobel Prize for this. By lowering glucose and glycogen levels we strengthen the Mitochondria. His speeches and interviews are on YouTube. Daryl has asked me not to post videos, but you can fid with a quick search.

Mike

[Spyder54 in reply to Spyder54]

“Never give up- Never give in”. eurekalert.org/news-release...

[Arcticfox44 in reply to Spyder54]

Thanks