Discontinue of Zoladex

[Andrevz]

At which stage can the Urologist decide that One may now discontinue having Zoladex inj. and is it possible for a medium term Period?

[Tall_Allen]

For advanced prostate cancer, you NEVER discontinue Zoladex completely, unless you have an orchiectomy. It may be possible to have vacations from it for limited periods, depending on your situation.

[Dan59 in reply to Tall_Allen]

Is it true that after many years on lupron/zolodex the body may no longer produce T , and at that point would lupron/zolodex not be nessecary? I have had only 1 zolodex in last 4 years, and that was just recently when t went to 44.

[Andrevz in reply to Dan59]

Hi Dan

Thanks for the Feedback, but I have been on Zoladex 5 years now, and the Doc told me that the Cancer cells build resistance against the Injection, sort of confusing, but also seems True

[Dan59 in reply to Andrevz]

It is tricky, if the body still produces t, than we need to get rid of it with lupron/zolodex. The thought is , though some cells may be resistant there is a whole lot more that are still responding to it.

[Tall_Allen in reply to Dan59]

That won't happen in every case - the testicles can come out of their induced coma at any time. But if the desire is to keep the testicles from producing T permanently, why not just have them removed? If you are on intermittent ADT and want periodic vacations from the side effects, then the non-recovery of your T production is not what you want.

[Andrevz]

Hi Nalakrats, interesting topic: Was just wondering if I could discontinue my Zoladex,at least for a period, and see if my Fatique and other side effects do improve. How does one determine if You can let go of HT.

Andre