Saw my MO today and after months of 0.04, my PAA came up to 0.7 3 Months ago and 0.21 today. She wants to see me again next month. Anyone have experienced a similar bounce?
PSA Rise 0.07 to 0.21 in 3 months. - Advanced Prostate...
PSA Rise 0.07 to 0.21 in 3 months.
I’ve been on Lupron, Abiraterone 1000mg/day and 5 mg prednisone per day.
Retest in two weeks.
There's nothing to be done until your PSA reaches 1 or 2
Thank you Tall Allen. I have read so many great posts from you. Honored that you responded to mine. Jim
Small PSA rises can be random fluctuations, and PSA below 1 generally means nothing is seen on scans which means there is little to check treatments against.
Still, if one has a dangerous, low-PSA type cancer with a metastatic history and with no current SOC medication, and PSA after being below 0.1 for many months rises to detectable say 0.2, wouldn´t a wish to be proactive call for a rapid treatment even if there is a clear possibility that this is unnecessary?
I hit my PSA nadir in February 2020 at 0.06 but my PSA started doubling every 3 months from May/June 2020, it slowed a bit in November 2021 and was then 8.0. My November 2021 CT scans show no mets. I’d hoped to get into a Lutetium trial but until I have at least 5 mets of the specified size I don’t qualify. My MO’s advice is clear – sit tight and continue Zoladex and denosumab and wait until I’ve got some targets to shoot at. I’ve been dropped from his monthly appointments list to the 3 monthly group. He thinks I’ll have some targets by September 2022. I’m feeling good and no symptoms – enjoy the ride while you can.
I can’t recall what my Gleason was but this is my first treatment regime.
Greetings JH,
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Good Luck, Good Health and Good Humor.
j-o-h-n Saturday 02/19/2022 12:24 AM EST
I would not consider that much of a bounce. That could be due to an inflammation in the prostate bed. Wait and see what the next PSA reading is.
If the next test confirm 0.2 That means Biochemical recurence BR so imperatively should know Where is the recidive Local or métastases consider Pet PSMA
At this Level of psa 0,2
Now if local BR so radiothérapy of the bed of prostate is considered +\_ hormonotherapy 3 or 6 months
Did ADT fail for him?
Inositol.
Nitric acid.
Sodium sulfite.
Potassium hydroxide.
Sulfuric acid.
Catechol.
These are the ingredients in Protocel and it was banned in the United States in 1989.
The only impression I have from that article:The patient does not want to do chemo or radiation so he is offered caustic industrial chemicals instead.