Melatonin vs prolactin

[Fatjoe97]

Hi there,

As stipulated in the picture attached and several of Patrick's exceptionally informative posts, it is patently obvious that melatonin seems to possess anticancer activity.

This is further supported by the 3mg melatonin study which greatly improved survival amongst poor prognosis prostate cancer patients.

However, I wanted to ask everybody's opinion on melatonin's ability to elevate prolactin. It seems that doses as low as 1-5mg can elevate prolactin (see study attached below).

Does anybody have any opinions on whether they experienced a prolactin increase/psa increase from melatonin?

P.S. I am well aware that all supplements contain risks and melatonin was suggested by one of the top Integrative MDs.

Do you think a dose of 3mg could cause hormonal issues with respect to prolactin? (I am well aware that most of the benefits are derived from higher doses).

pubmed.ncbi.nlm.nih.gov/336....

karger.com/Article/Abstract...

[Justfor_]

My (only) two data points seemingly support a linear relation, but more points are needed for anything tangible:

July 2020: 10 mg Melatonin daily -> 3.0 ng/ml Prolactin

January 2022: 20 mg Melatonin daily -> 5.5 ng/ml Prolactin

[Fatjoe97 in reply to Justfor_]

very interesting thanks for sharing!

[LearnAll]

I have been taking Melatonin 10mg every night for last 2 years. Prolactin levels have been normal. BTW, I also take VITEX FRUIT (natures way) caps off and on to keep prolactin level low.

[Fatjoe97 in reply to LearnAll]

Thanks so much for highlighting this, really appreciate it!

[Fatjoe97]

Thanks so much for your advice really appreciate it! Will look into L-dopa

[j-o-h-n]

Hello Fatjoe97......If you're going to look into L-dopa look up my ex-wife....and btw here it comes:

Please tell us your bio. Age? Location? When diagnosed? Treatment(s)? Treatment center(s)? Scores Psa/Gleason? Medications? Doctor's name(s)?

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THANK YOU AND KEEP POSTING!!!

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 01/20/2022 8:51 PM EST

[Fatjoe97 in reply to j-o-h-n]

always love your humour lol !

sure no worries will update this info shortly

have a great day!

[j-o-h-n]

Thank you sir, enjoy your evening/sleep.....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 01/20/2022 11:16 PM EST

[Stoneartist]

I think you need to monitor the time of day you take the blood sample - looks like concentrations vary considerably throughout the day

[RonnyBaby]

I've been taking Melatonin for years - (1/3 of my adult life).

I do at least 30 mgs before bedtime.

I see NO personal evidence that my PSA has ever been affected.

I'm undetectable again, after a recurrence that started 2 years ago.

My original Dx was 5 1/2 years ago - I've gone 'undetectable' TWICE that lasted

a total of around 3 years and counting (I'm on an ADT monotherapy).

I'm doing well and remain optimistic - I've followed the pros and cons and the debate.

It becomes a personal decision which can be monitored on an ongoing basis .....

[dhccpa in reply to RonnyBaby]

Your experience is encouraging. You have bone Mets?

[RonnyBaby in reply to dhccpa]

ONE (L5) was found during my last PSMA scan, BUT it appears to be shrinking - it might disappear - time will tell .....

[dhccpa in reply to RonnyBaby]

Thanks

[dhccpa]

Do you take Mucuna capsules? Tinctures? Teas? Thanks

[BillyJack25]

What would be considered a high level of prolactin?? My recent prolactin test came in at 7.4.