Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein

[cesces]

A new Penn Medicine study shows how anti-androgen drugs disrupt key receptors required for viral invasion of cells.

Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press’s iScience.

Researchers show how two receptors — known as ACE2 and TMPRSS2 — are regulated by the androgen hormone and used by SARS-CoV-2 to gain entry into host cells. Blocking the receptors with the clinically proven inhibitor Camostat and other anti-androgen therapies prevented viral entry and replication, they also showed in lab studies.

Hormone Drugs May Disarm Coronavirus Spike Protein and Stop COVID-19 Disease Progression.

scitechdaily.com/hormone-dr...

[Chask]

I seem to recall that in the early days of the pandemic - early 2020 - it was found in Italy that men with prostate cancer seemed to be infected at a far lower rate than other men. While there was no real study or proof, I think that was put down to the fact they were being treated with ADT medication.

[V10fanatic]

This would make it the only good side effect of ADT.

🤨

[Hidden]

I tried to tell this to my new pc specialist Gelman . He said “ Get the vaccine “! Like I’m a jackass for not already doing so. My better half is opposed to it.

[cesces in reply to Hidden]

Why would you not take the vaccine?

[Hidden in reply to cesces]

I can . Wife is opposed

[treedown in reply to Hidden]

My wife was not thrilled about getting it. I did without issue, she did and had a headache for 4 weeks and was told not to get her second shot for a little while. Glad I said it was her choice.