Father dx 2017, Gl 9, T4N1M1, PSA 944. ADT till summer 2020. 4 rounds of Docetaxcel in aug- dec 2020. Dec 2020 started Zytiga. It working pretty well, but we are having some issues with our doctor, hospital burrocracy. So he have just 4 days pills left (with half dose and breakfast already) and it`s looks like we will not get new bottle for few weeks.
Is it bad or maybe even good? like intermittent phase?
I am not a fan of intermittent ADT drugs. Stopping could allow a new cancer cell line to find a work-around.
We have nothing to report. Doctor didn`t ask for PSA for 3 month. Finaly i could convience him and yesterday he finlay did PSA testing. He feels much better with every month. Looks better, much more energy, positive mood and even started to excercise. He will have scans, analyses and etc next few weeks, but as i understood right they will not give him new dose of Abirateron, before results will came good.
I just hope that PSA is lower that 10 
Last time his PSA was lower than 2 about 3 years ago...
Yesterday almost get banned from one group in Facebook after arguıng wıth doctor about PSA. SHe made post when she explain what kind of treatment and when it is better to use. And that they are making changes in treatments afther PSA get more that 2, 5. But why they didn`t say nothing when PSA was around 45 for 2 years for my father? And she reply that it`s for people with "good prognosis", and when PSA at dx is 944 it is "bad prognossis". They just do polliative therapy.
I wondered about Zytiga half life. I forgot to take mine for one day and and was slightly concerned. Couldn't find any "half life" info. Thanks!
Get a new MO
would love to, but unfortunatly father lives in small town and just don`t have other options. It`s main public hospital
It's not good, but what can you do? Why did you only have 4 rounds of docetaxel? it's usually 6.
At the begining of chemo PSA was 202, then dropped to 42, but after 4 round it was 250 and next week already 305. So they switched to Abiraterone.
Just got the PSA results 80,69. Probably in begining of Dec 2020 it was around 600 probably. Is it good drop in 4 month? I was hoping to see something more near 10-20.
Down is always good.
Just got PSA result 80,69. And ALP 336. We are far away from undetectable.
But it`s looks like Zytiga is working. It was much more higher in Dec. Probably around 600. It was raising pretty quickly.
Maybe it is worth a longer drive for a new MO. Didn’t see any mention of genetic testing.
I am planing to bring him to Moscow in may. All good and progressive doctors are here, unfortunatly, as genetic testing.
Dont panic. It may even help having a gap and extend the time to effectively use Zytiga. See refs by Gatenby et al, in a recent post by me.
Father’s CRPCa Failed chemo (Cabazitaxel,Docetaxel) and Failed LU177
K I S S, yes trying to keep it simple. A Lupron vacation after 2 yrs on & Abiraterone(250mg) & Prednisone 5mg? Yes or no?
Newly Diagnosed - Advanced Stg Prostrate Cancer.
What next?
