Post SRT + ADT PSA

[Lissy300]

Hi,

My father (64) has prostate cancer - G4+3 pT3a N0 M0, RP 2017, pre surgery PSA 5.7, post op undetectable until 30 months when went to 0.12 to 0.16 in about three months. CT and bone scan negative. Salvage RT to prostate bed and combined ADT (casodex and GnRH) started at this level (0.16). RT was from August-October and ADT just finished a week ago. Three months in (around October) his PSA was 0.01. Now, a week off ADT and three months out from SRT, his PSA is 0.16 again. What does this mean? So worried.

x

[4Rosebud]

Try not to worry and be positive don't panic. My PSA doubled the first post test. It's been 6 years, All of those treatments reek havock on your body.

What else is he doing. has he changed his diet, exercising, stopped eating sugar, processed food, and GMO's Western Medicine doesn't address these and my success has all been based on this..

go watch The Truth About Cancer, and Chris Beat Cancer Websites. Read about Gershon it's radical but effective, its all about cleansing and rebuilding.

His body is fighting cancer he needs every bit of strength he can get for that fight..and keep his immune system strong, keep an open mind.

One of the most important things is to keep your stress level down..be happy..and positive..it's so hard but really important..attitude determines altitude.

[Tall_Allen]

If his PSA keeps increasing, there is a clinical trial of intermittent use of second line advanced hormonal agents that I like a lot.

clinicaltrials.gov/ct2/show...

[Justfor_]

Depending on the extent of the irradiated field (prostate bed - whole pelvis) there is a high chance that the -prior to RT- PSA origination was distant. In such a case a sRT isn't helpful, but rather harmful due to SE and late toxicities. That is why in my case I will first take a PSMA PET/CT and if it comes clear of distant lesions, then proceed with the sRT. Silly or old school doctors parrot that the PSMA pet scan at PSA <0.2 is useless, but numerous papers show a positive detection rate ranging from 30-60%. There is not much your dad can do now apart from monitoring his PSA and when it reaches 0.5 (that silly doctors understand as a cut-off value) take a PSMA PET/CT, so as to get a better view of where the PSA comes from.

[Spyder54]

Look into Gallium 11 PSMA PET Scan. Just approved Dec 1st. Can find the hard to find Mets, and then be radiated with little side affects. Then PSA should drop again. On YouTube search Dr Kwon Mayo clinic. He shows many examples. Your Father should be fine. Im working hard to achieve the low numbers he already had. Best of luck!

[DonUSNA73]

Who is on his health team? An oncologist who specializes in prostate cancer? If not that would be my first action (I was also 4+3 and T3a N0 M0). Similar treatment but had Zytiga instead of Casodex in combination with Firmagon all for 18 months as recommended by my PCa oncologist. Have been (knock on wood) < .01 for 6.5 years...Don

[j-o-h-n]

Please tell us your bio. Age 64 Location? When diagnosed? Treatment(s)? Treatment center(s)? Scores Psa/Gleason? Medications? Doctor's name(s)?

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Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 01/26/2021 6:44 PM EST