When Lu-177

[Fightinghard]

Sounds like trials have shown some great success stories.

Anyone have insight as to when Lu-177 may become approved/available in the US?

[Tall_Allen]

They haven't even published any findings.

[Fightinghard in reply to Tall_Allen]

Thanks Allen!! Guess I read all the comments here and was excited!!!

You always have the latest. Appreciate your help

[ctarleton in reply to Fightinghard]

For ballpark planning, here's a link to the Phase 3 VISION trial, showing objectives and planned completion dates. Publications and any US FDA Approval determination would likely add some more time.

clinicaltrials.gov/ct2/show...

If you may be thinking of a particular site for future treatment in the USA, the trial participating locations would already have some experience with some clinical trial patients by then.

[vforvendetta in reply to Tall_Allen]

I guess I could "Duck Duck Go" this on my own, but off the top of your head do you know the timeline for it being offered in Canada?

[Tall_Allen in reply to vforvendetta]

Same as the US. The data from the VISION study has to be published before it will be approved.

[vforvendetta in reply to Tall_Allen]

As always, thanks Tall_Allen. I can't state enough how grateful I am for your input here.

[Schwah in reply to Tall_Allen]

Are you hearing any preliminary findings (good or bad) thru your grapevine TA?

Schwah

[Tall_Allen in reply to Schwah]

I don't think they have compiled any data yet.

[6357axbz in reply to Schwah]

Hopefully there will be sufficient data to cover most of us, i.e., hormone sensitive, hormone resistant, pre and post chemo etc.

[6357axbz in reply to Tall_Allen]

Does Lu177 kill microscopic cancer cells or only those tissues expressing PSMA?

[Tall_Allen in reply to 6357axbz]

Lu-PSMA-617 kills all cells expressing PSMA, whether microscopic or part of larger tumors.

[6357axbz in reply to Tall_Allen]

So if no tumors are present large enough to be picked up by a psma pet/ct scan how would we know how much benefit it would have?

[Tall_Allen in reply to 6357axbz]

You would not qualify for the drug.

[tango65]

They have not approved the Ga68 PSMA PET/CT yet, despite of published studies and requests for the approval.

It is going to be a while longer for the Lu 177 PSMA PET/CT to be approved in the USA.

It is a shame since it seems that it is more effective in patients treated earlier before chemo is required.

jnm.snmjournals.org/content...

Ga 68 PSMA and Lu 177 PSMA are routinely used in Europe, India, Australia, South Africa etc. Both are effective, well tolerated and have a low incidence of severe side effects in patients without extensive bone marrow infiltration.

[addicted2cycling in reply to tango65]

Sadly >>> $$$$$$$$$$$$$$ + TRAVEL = AVAILABILITY

My Fed-Up reply for here in the USA = soon, very soon, really it will be soon, like a miracle it will be here, maybe by Thanksgiving just not last Easter ?????????

not a happy camper this am :0( -- just hoping for everyone that today is better than yesterday and tomorrow will be better than today

[mcp1941 in reply to addicted2cycling]

Thanksgiving 2025 ???

[addicted2cycling in reply to mcp1941]

lol

[louschu]

I was in phase 2. My understanding is you had to be really progressed to qualify for phase 3 which creates its own problems. I lost a friend who was getting the drug bu