Lupron Depot 3 mo. USA drug shipmen... - Advanced Prostate...

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Lupron Depot 3 mo. USA drug shipment shortages?

ctarleton profile image
27 Replies

Got a phone call from my Oncologist's office today. They mentioned a temporary widespread USA shortage of the Lupron Depot 3 mo. drug that I've been getting for years.

A little noodling around on the Internet confirmed that this could be the case.

accessdata.fda.gov/scripts/...

They are looking into getting me an available Lupron Depot 1 mo. as a temporary work-round, or possibly doing a temporary switch to an available Eligard.

Just thought I'd mention it in case anybody else may seeing this kind of thing happen as the "medical drugs world" is churning at a high rate in these days of COVID-19 and related matters.

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ctarleton profile image
ctarleton
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27 Replies

Wow, what's next? I have always been given Eligard.

erjlg3 profile image
erjlg3

Thanks so very much for the info!!!

I hope if switched that everyone will only get the 1 month injection until they see if they will have any bad side effects.

🌻Jackie

Olivia007 profile image
Olivia007 in reply toerjlg3

It’s the same drug according to our doctor

SPEEDYX profile image
SPEEDYX

My MO switching me Eligard...also FDA probably will approve new pill to replace lupron by end of year

LearnAll profile image
LearnAll in reply toSPEEDYX

Rolugoli tablets (luprolide tablets) might be available by july 2021. But do not know how much the RoluGoli tabs will cost ? Probably a hand and a leg.

SPEEDYX profile image
SPEEDYX in reply toLearnAll

What else is new....of course my MO didnt mention cost.

Gearhead profile image
Gearhead

This is consistent with my experience yesterday when I was in for my every-3-months Lupron injection. When the nurse went to get the Lupron, she returned with Eligard. She asserted that they are the same drug. (And my subsequent research confirmed that they are both Leuprolide. Let me know if I've misunderstood something here.) I found it interesting that, while Lupron and Eligard both have separate solutions that must be mixed before injection, the way they accomplish that is somewhat different. I'll explain in the unlikely event that anyone other than me is interested in that level of minutia.

in reply toGearhead

What did you think of the Eligard shot as compared to Lupron? I find it initially more painful, but then the pain goes away quickly.

6357axbz profile image
6357axbz in reply to

I’ve had plenty of both. I think they are the same. Pain depends on the skill of who gives the injection. The larger the dose the more pain the next day.

SPEEDYX profile image
SPEEDYX in reply to6357axbz

So True

Gearhead profile image
Gearhead in reply to

I have never found the Lupron injections, or this recent Eligard injection, to be painful. And I'm not trying to be macho here. I think ADT has removed that tendency.

Olivia007 profile image
Olivia007 in reply to

Yes my dad complains of the painful injection every three months and then he claims the pain lingers on after that???

BillNIttles profile image
BillNIttles in reply to

Had the Eligard shot Wednesday. I found it surprisingly painful, since Lupron has never bothered me at all. I still have a slightly tender knot on my belly.

in reply toBillNIttles

I take 2 extra strength Tylenols ahead of time and that takes the edge off it, but yeah it hurts for sure. To me it's kind of a burning feeling, but goes away fairly quickly.

BillNIttles profile image
BillNIttles in reply toGearhead

Got my Eligard shot Wednesday and they had to figure out how to mix it for me. They keep it for backup, and we thought that Eligard might have a longer shelf life than Lupron. Is that true?

I had 3 month injections from May 2004 to February 2010; either Lupron or Eligard, which ever was available. I preferred Eligard. Initial sting with no lingering soreness. Lupron always was dire for several days.

GD

in reply to

I've had both too and prefer Eligard for the same reason. I found Lupron to be a literal "pain in the ass" for days after.

j-o-h-n profile image
j-o-h-n

As most women would admit.... it depends on who's doing the injecting.........

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 08/15/2020 10:57 AM DST

Yank66 profile image
Yank66

DH had Eligard last week because of Lupton shortage. Injection was given in the stomach instead of the hip. He said it stung more than Lupron. Other than that, no difference.

That happened to my husband on Wednesday. They gave him Eligard. He said he likes that better. It was given in the stomach and not near the pain as the Lupron for a few days after. He also said it was nothing like the Firmagon. Think he will stick with the Eligard.

in reply to

Same for me this past Wednesday.

monte1111 profile image
monte1111

I've always had 6 month Lupron injections. Maybe they'll have this figured out by December. In the hip, so sore hip for about 3 days. Slow injection makes for less pain. Anyone have a clue as to why I only have 6 month injections. Just a money saver? For me, it seems to be working just fine. The belly fat injection sounds attractive to me. But don't guess I'll change alligators in midstream.

GAdrummer profile image
GAdrummer

Monday the urologist said that due to the continuing response to Keytruda (undetectable PSA & normal scans), he would give my husband a six month vacation from Lupron and re-assess then. Now I know why....

ctarleton profile image
ctarleton

Here's an article describing the probable root cause for the back-ordering of Lupron.

Takeda's Hikari, Japan manufacturing plant stopped Lupron production after a June 2020 inspection involving some very small rubber particle contamination in certain equipment. The European market may not be impacted since their supply comes from a different plant in Osaka, Japan. Japan and the Americas are seeing shortfalls. Re-certification could last into the Fall of 2020.

The production of the same active ingredient drug Eligard, made by a different manufacturer in a plant in the USA, is being ramped-up in an effort to fill the temporary gap.

These temporary shortfalls could impact patients dealing with prostate cancer, breast cancer, endometriosis, uterine fibroids and early puberty.

fiercepharma.com/manufactur...

BillNIttles profile image
BillNIttles

Yes. I get monthly Lupron and this past Wednesday I got a surprisingly painful Eligard shot in my belly. Lupron never hurt at all. The nurse(s) dealing with me had to figure out how to mix it up correctly. Turns out, they keep Eligard as backup for a situation like this. Apparently it has a longer shelf life?

My Eligard injection was always in the upper buttocks. Really doesn’t matter if stomach or upper buttocks. What does count is adequate amounts of subcutaneous tissue that does not have excessive hair etc.....

GD

timotur profile image
timotur

Last week, I had my monthly Lupron shot at UCSD, no mention of shortages. Next month, I just hope when I show up for the last of the 18-mo regimen, they don't tell me all they have left is a 6-mo dose...!

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