If Proton Therapy is successful can I... - Advanced Prostate...

Advanced Prostate Cancer

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If Proton Therapy is successful can I get off of Xtandi?

Bobcat64•

5 years ago•13 Replies

Starting proton therapy next week. RO thinks remission and possible cure. If so can I get off of Xtandi.

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Bobcat64

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13 Replies

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Magnus19645 years ago

If your PSA stays low I would stay on xtandi. Why quite a drug that is still working.

Fiddler20045 years ago

If PSA is good but you're having troubles with Xtandi side effects you may be able to reduce the dose from 160 to 120 or even 80mg / day and still have it effective in treating the cancer. Ask your oncologist.

Bobcat64• in reply toFiddler20045 years ago

PSA. Continues to rise.

Fiddler2004• in reply toBobcat645 years ago

Have you been on / tried Lurpon or other similar ADP thherapies?

Tall_Allen5 years ago

There is absolutely no evidence that protons (or any other therapy) can cure you after there are distant metastases. Treating PSA is not the same as treating the cancer. We know that Xtandi extends life, there is no evidence that metastasis-directed therapy extends life. I'm not saying don't do it, just have reasonable expectations and don't give up on what we know are life-preserving therapies.

Bobcat64• in reply toTall_Allen5 years ago

On Xtandi for 3 months and PSA continues to rise 18 to 20 to25 I must have got my hopes up have only one Mets.

Bobcat64• in reply toTall_Allen5 years ago

Just had call from RO cancer has spread to pelvis and several other areas. He suggests 4 weeks of proton and stay on eligard xgeva and xtandi. What do you think?

Tall_Allen• in reply toBobcat645 years ago

I'm trying to figure out what your situation is from previous posts - there's nothing in your profile. Has your prostate been treated with surgery or radiation? How many metastases in total have been discovered (it doesn't matter if they have disappeared), and where are those metastases?

Bobcat64• in reply toTall_Allen5 years ago

Thanks I hope to talk to RO this pm. Will update

Bobcat64• in reply toTall_Allen5 years ago

Completed proton.but what concerns me is that MO at proton said I had 4 Mets both pelvis and 2 spine. My local MO read the same film and only 1 met right pelvis. How can two professionals read the same film and be that far apart.

Tall_Allen• in reply toBobcat645 years ago

You should be relying on what the radiologist report said.

j-o-h-n5 years ago

cure? Where have I heard that word before? I suffered from terrible migraines but was cured when my wife left me.... (cure = nada)

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 05/03/2020 6:02 PM DST

billyboy35 years ago

It matters little as to whether one guy sees one met, the other sees four, the fact is that you cancer has spread, a cure is now impossible and Tal is right, do what works for as long as it does and quite playing around. The clock is ticking so make up a bucket list and live large man, spend time with loved ones or the boys at a bar, but do NOT sit and try to outguess your pc.