Recently diagnosed Stage 2 G7 (4 cores 3+4). I want to avoid cut-burn-poison therapies if possible.
Keto diets are being used as adjunct therapy in other cancers and in trials for PCa per my research. Dr. Tom Seyfried of Boston College has new theory of cancer as a metabolic disease, not a genetic disease. This is based on the Warburg Effect, that cancer cells use fermentation for energy, not normal mitochrondrial energy pathways.
Seyfried promotes press/pulse therapy for brain cancer; keto diet as pressure on cancer, pulses of hyperbaric oxygen, chemo or radiation as pulses to kill cancer. He says keto diet stresses cancer and allows lower dose chemo and radiation.
PubMed papers say early stage PCa may *not* be a candidate as there is a different cancer cell metabolism, but late stage PCa may be susceptible.
Has anyone tried keto press/pulse for either early, intermediate or advanced PCa?
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"Cancer, above all other diseases, has countless secondary causes. But, even for cancer, there is only one prime cause. Summarized in a few words, the prime cause of cancer is the replacement of the respiration of oxygen in normal body cells by a fermentation of sugar."
Warburg believed that for the rest of his life, but I think that few in his field now regard glycolysis as the prime cause of cancer. In any event, PCa doesn't start out with a preference for glucose. As Dr. Myers has said, good luck getting insurance to pay for a fluorodeoxyglucose (FDG) PET scan.
PCa does not inevitably switch to glycolysis (from fatty acids) as it advances. But any mets that show up via FDG PET do have a greater uptake of glucose & might be controled via a ketogenic diet. I suspect that PCa would adapt, though.
I don't buy into Seyfried's view of cancer as a metabolic disease, in the sense he means, but I do regard PCa as another symptom in the metabolic syndrome [MetS]. The prudent thing is to follow the restrictions of a diabetic diet - which is definitely not a high-carb/low-fat diet. The Mediterranean diet (40% fat) seems to work well against MetS, & is not onerous to follow.
Would an even lower carb intake be better? Dr. Steve Feedland has studies using very low levels of carb, but few would tolerate the lowest levels indefinitely.
"I don't buy into Seyfried's view of cancer as a metabolic disease"Why don't you? Could you explain?
I was diagnosed a bit over a year ago, and at that time immediately changed my diet to keto. It was so easy back then to get and stay in ketosis, but now after a year it is a lot harder, almost impossible; I believe it's the prednisone/zytiga medications that work against it. I have found it fairly easy to keep carbs less than 20 grams per day, but the hard part is trying to keep protein low as well. A therapeutic keto diet is 20 grams of each carbs and protein, and that's practically impossible if you exercise much.
But, If I do go to the gym and burn 800 calories, I know my body is burning up the glucose first. I believe the biggest benefit of keto is keeping the weight off.
I tried many things to help at first. Vegan , cannabis oil, supplements and herbs. I was fortunate to have the time to do it as I was like you and on surveillance . Nothing worked for me. I ended up having surgery. I can only speak for myself but you can only play around for so long until the shit hits the fan. I have been cancer free for over a year now.
I was on a strict keto diet for many years ( 18 ) before my diagnosis.... first diagnosis was stage 4 and part of my first oncologist visit included my hospice crew due to severity of diagnosis. My basic instinct was that keto had no benefits or even may have promoted my disease.
That’s my own experience with keto, not scientific... just instinctual.
Science has found that once a cancer is diagnosed, no diet will make it go away. There is wishful stuff on the internet about different foods and effect on cancer. They all come from observational studies showing correlation but cannot prove cause and effect. Changing your diet after a cancer diagnosis will not slow or reverse the growth of cancer, but if it can help you feel better then go for it! It can make your body stronger and more able to fight the disease.
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