Subcorneal pustular dermatosis

[Frigataflyer]

I have been on Lupron for nearly a year and have experienced its known side effects plus a variety of “skin conditions. Recently, with the help of Google, my dermatologist told me I had Subcorneal pustular dermatosis which is “a rare, chronic, relapsing, bullous condition, characterised by blisters that become filled with pus. “ (pcds.org.uk/clinical-guidan.... Although it is considered a “disease”, It is of unknown aetiology, and non contagious, does not affect longevity and apparently its only downside is cosmetic. The pustules have an interesting characteristic; the pus occupies only the bottom half of the pustule

I am curious as to whether anyone else in this group has experienced this.

[tango65]

Lupron and similar drugs could cause allergic reactions. I had one with Firmagon but it did not affect the skin. The dermatosis you have may be associated with a gammopathy. They could study if you have some form of MGUS (monoclonal gammopathy of undetermined significance). This condition is more frequent in people 70 and older.

mayoclinic.org/diseases-con...

ncbi.nlm.nih.gov/pubmed/158...

[Frigataflyer in reply to tango65]

Tango65. Thanks for your reply. I guess that subcorneal.... is independent of PCa and Lupron.

[tango65 in reply to Frigataflyer]

I do not know but since it may be associated with a gammopathy, they have to rule it out. MGUS is in general a benign condition but in a small % of patients it could progress to multiple myeloma, If there is a MGUS they have to follow it closely, at least every 6 months.

[j-o-h-n]

youtube.com/channel/UCgrsF4...

She's good looking and smart...

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 11/16/2019 11:04 PM EST