Hi all, my husband who is 5 or so years post surgery and adjuvant radiation for a Gleason 9 had a BCR starting in January 2019. Since then his PSA values went up as 0.22, 0.44, 0.35(different lab and not in the sequence, he had a PSMA pet scan that showed nothing), 0.5, and 0.521. These were all 3 month values except the 0.35. He is not taking any medication and never had any, just vegan diet and exercise. We are obviously pleased but I am wondering what is happening? Anyone see this before?
Thank you.
Written by
FSB12
To view profiles and participate in discussions please or .
Detectable but low PSA that fails to increase may represent residual benign glands left behind at surgery. [....] Another possibility is that these low levels originate from tissue other than prostate. PSA expression has been seen in cells of periurethral glands, breast, colon, kidney and liver. It is also possible that these nonprogressing PSA levels represent a dormant focus of cancer, either inside or outside the operative field. There are many patients on watchful waiting treatment protocols whose prostate is known to harbor cancer but in whom PSA never progresses.
I’ve done a 360 flip into nutrition ,diet and staying active . My wife assures that I do . Left to my our accord ? Who knows what I’d be doing . I probably would not have survived thus far . I need someone to tell me to get up ! And get active .. with no t I could sit down and fade into dust . Thank god for our partners help . 🎃
Some think the cancer is "preparing the soil" for future growth during this phase. I have no idea what is happening immunologically during this phase- whether it is becoming more resistant or not.
Keep up the good lifestyle and another decade is possible .. 💪😎
2006 Recurrence and salvage radiotherapy 45 Gy + Casodex 150mgx1 for two years. For the first two years psa was about 0.01 and later it increased to level 0,6 and was stable until 2017 then it gradually increased to 2.0 in 2019 . PSMA Gall 68 and MRI showed nothing, but I started taking casodex 150 x 1 and now participated in the Atorvastatin 80mg/placebo study for a month. My psa is now 0.48.
Thank you for your story. So you or your doctors thought that 2.0 was too high to ignore even with the good scan? I am not clear on what would be recommended to my husband if he progressed like this.
My urologist at psa level 2.0 sent me for PSMA Gall 68 and MRI tests. Other tests were also done, e.g. urine tests, exclusion of cystitis or prostatitis. All clean. Then my doctor wanted to wait for the psa to be above 5 and then start hormone therapy. I asked for a casodex (Bicalutamide) prescription because I thought it was a better choice. There will always be time for hormone therapy. For now, I`m buying time and corresponding with patients who are taking "repurposed" medicines like metformin, mebendazole, fenbendazole, statins, malaria drugs etc....
There is a difference between casodex and other hormonal drugs like lupron and others. In 2006, before taking casodex, I had a single dose of radiation around 10 Gy for each breast. This radiation prevented pain and breast growth. For two years of taking casodex I had no side effects. I don`t have them now. Casodex does not block the production of testosterone in the body and therefore does not cause such effects as decreased in libido, heat waves and profuse sweating, fatigue etc. .... I don`t know how long casodex will work for me, but I have plan "B" and plan "C" (with repurposing drugs). In this forum, many patients also take repurposing drugs along with standard treatment.
The best effect is when the radiation is done two weeks before starting hormone treatment. If the radiation is done during treatment, the result is weaker, but it reduces enlarged breasts.
Some patients take medicines for breast enlargement and pain.
I did not see if your husband had full field or local bed Adjuvent Radiation. If it was just local bed, he may benefit from full field lymph node coverage. Should discuss with your MO and RO
He had local prostate bed radiation. So far his MO at Hopkins seems happy to wait. So we are not really clear on what to do. The RO would wait for higher PSA also.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Are we jumping the gun here, can we see if Zytiga settles my PSA first before hitting me with Chemo Again?
Dad's PSA now 1800..nothing works..Is this the end??
5th Xofigo treatment done PSA is at 692.32
Rising PSA after RP, how common is this?
Is this a PSA flare caused by chemo?
