DX in March 2019 stage four, Gleason 9, one doctor indicated that with my 7 mets and lymph invasion that it was not good. I thought things were soon coming to an end. However, at the recommendation of a friend I sought out a MO at the Siteman Cancer Center in St. Louis
After meeting him and discussing options he started me on Cosadex for two weeks, then went to Lupron. Zytiga with predisone.
Results yesterday PSA 4.4 down from 99 in March, T <5 down from 460. I am pleased, happy and thankful for modern medicine, this web site and good advice given, plus J-O-H-N 's good humor.🤠
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Drphil1938
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You are right that "it's not good" but that is precisely what has been successfully treated in many of us and why we simply have a chronic condition, not a death sentence.
Great attitude DrPhil...most of us are here due to modern medicine ..... great results so far ...keep on trucking . Welcome to the club. And yes , j-o-h-n is our best asset .. Carpe diem !
Why is your MO Running through so many drugs in a short time period? It does not seem like you were any of them long enough to base an opinion as to whether they were working or not.
Obviously one or more are but you may not have any of those other drugs as a fall back position. I would question your MO.
I am not qualified to question his reasoning, his goal to quote: "we want to put this stuff to sleep as quick as we can and then try to keep it there." This approach is exactly what I want, so I won't argue with him.
The standard of care for hormone sensitive PC is ADT plus Zytiga and prednisone or ADT plus chemo. They give Casodex for 2 weeks to control the testosterone surge caused by Lupron . After the testosterone surge, Lupron will cause inhibition of testosterone production by the testis .
You had an excellent response to treatment. Congratulations. Best of luck with your journey.
I don't want anyone to lose confidence in their doctors. It just seems that having a patient change three different drugs in as many months is not enough time on any of any of them to make a judgment on the efficacy of any of them. Unless this is a new protocol I don't know about.
I started on Cosadex for two weeks, then a 3 mos lupron injection, 30days later PSA dropped to 18. We stopped cosadex and went to xytiga with predisone, we are now SOC .with results I gave earlier. I understand what you are saying. That we may be burning some bridges early in treatment but I am fine with where we are. I am coming up on 81 and these are bonus years. I dont want to leave any on the table.🤠
Everyone should read your amazing history. you’ve Squeezed every bit of life from each treatment. Maybe it’s different when you start at age 81 but watch out for side effects.
Side effects have been minimal, some fatigue and five or six good hot flashes each day. Also a good martini 4 or 5 times per week keeps me relaxed and loving life.🤠
Try looking up the Stampede trial. Thanks to those in that trial I am now 18 months <0.01 having started with 3 positive nodes and multiple bone mets. There is no "wait til later" treatment. We hit hard now and hope it works. If/when it doesn't, thankfully there are new things to try then.
Drphil: My starting point (i.e., mets, PSA, Gleason) was similar to yours, my medications sequence is the same, my rate of PSA decrease is similar, and my side effects are also minimal. Our main difference is that for me, a glass of good cabernet 6 or 7 times per week is what helps keep me relaxed and loving life.
I'm on the same meds as you are for about 20 months now. Meds in lymph nodes, bones and spots on organs. Psa was at 800 now is under .1 getting a Lupron shot every three months too. Also no pain. So glad for you that your treatments seem to be working too. Hang in there
That's great news! Hang in there brother! Sounds better than having chemo. My situation is very much the same, found out in April that I have stage 4 and mets. Just had my 4th chemo infusion two days ago. My PSA is down too, and I'm feeling food about life. Thanks for sharing. Always great to hear positive outcomes.
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Keep up the good fight!!!
FDA detained meds that are not mine
Yes, we are more at risk from Covid-19.
What are your thoughts on Pain Control
Hi we are new to this site
Lupron only after 4.5+ years
