Yes, we are more at risk from Covid-19. - Advanced Prostate...

Advanced Prostate Cancer

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Yes, we are more at risk from Covid-19.

ppulatie profile image
15 Replies

Hey everyone. Just wanted to present this article out of the UK. There had been discussion about whether we are at higher risk of death from Covid-19. Appears we certainly are.

dailymail.co.uk/sciencetech...

BTW, PSA last week while on Xtandi was .65, down from .88 in March. Still winning!

Pat

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ppulatie
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Tall_Allen profile image
Tall_Allen

You misunderstand. "Low testosterone" is not the same as "no testosterone."

ppulatie profile image
ppulatie in reply to Tall_Allen

Not willing to chance it.

Tall_Allen profile image
Tall_Allen in reply to ppulatie

No one should risk exposure. But the data show that men on ADT who get the disease are less likely to die of it. So men taking ADT should not stop during the pandemic.

dac500 profile image
dac500 in reply to Tall_Allen

Do you mean that the increased risk of dying from Covid-19 does not apply to no testesterone (castrate level)?

Tall_Allen profile image
Tall_Allen in reply to dac500

Correct.

SooHwa99 profile image
SooHwa99 in reply to Tall_Allen

So what about those of use who may have just stopped ADT. but are still at a castrate state? Are we at more or less risk? And when our testosterone starts climbing again will we be at greater risk since we will technically be at a low T level?

Tall_Allen profile image
Tall_Allen in reply to SooHwa99

You are fine until testosterone rises.

noahware profile image
noahware

Even though there may be some overlap, the "we" that are posting here is not exactly the same group of men referred to in the article. Men with low-T covers a spectrum that would include both men with and without PC, and there is no indication that the group studied includes any men on "no-T" ADT regimes.

ppulatie profile image
ppulatie in reply to noahware

True, but don't want to risk it. Too much is still unknown according to a doctor friend who was a former virus researcher at Cal Berkeley long ago.

noahware profile image
noahware in reply to ppulatie

I agree much is unknown. But not sure what you mean by "don't want to risk it." I think each of us is at an unknown level of risk regardless of our T-levels. The evidence right now seems to point to castrate-levels of T (not just "high" or "low") as potentially lowering risk, from what I understand.

kryciakrycia profile image
kryciakrycia

Quite the opposite. In the last few days a number of articles from reliable sources appeared, showing that ADT (= low or no testosterone) may very effectively protect against Covid-19.

My repeated respects to Tall_Allen. He was right again.

The Italian study published a few days ago in the Annals of Oncology cited by many sources:

medscape.com/viewarticle/93...

Is it really LOW testosterone or NO testosterone?

Question: How fast (if at all) does the testosterone level return to normal after, say, one month ADT treatment - pills of course, not injections?

ppulatie profile image
ppulatie in reply to kryciakrycia

ADT uses the same type of mechanism, targeting receptors on PCA cells that the C-19 does on the Lung Sac cells. The question then becomes as to whether the same type of receptors exist on both types of cells.

All I know is that I am not going to risk going out in public even with reopening until much more is known, and that my docs think I am clear.

in reply to ppulatie

That’s the safe bet.. ✌️

I'm at risk from my wife smoking some bad weed, losing her mind and killing me for the insurance money. Covid -19 is 3rd or 4th on my worry list.

j-o-h-n profile image
j-o-h-n in reply to

Don't forget that young handsome. muscular, tan, pool boy she's been eyeing..... (could be reason number 1).....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 05/14/2020 6:13 PM DST

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