For all those in treatment with liver Mets...

[DSEE]

I am undergoing the second round of taxotere- 2nd infusion tomorrow-

First round was 2016 then Mets to liver showed up 3-19 and increased by June so taxotere began again.

Anyone with like treatment protocol please tell me results after last taxotere infusion.

Was it successful for stopping growth and for how long?

[GP24]

Tango, your links do not seem to work.

[DSEE]

I am not looking for other treatments but rather if others with liver Mets have experience a second run of doxetel ( taxotere) and what the results were-

Did taxotere 2016 and now-

[tango65 in reply to DSEE]

Just to let you know of other possibility in case it could be necessary. Something to discuss with your oncologist.

[RustyDakota]

I recently finished a second course of taxotere for the treatment of liver mets. Had a good PSA drop for the first 4 rounds, then it started going back up. Scans showed that the liver mets shrunk significantly. We'll see how long that lasts. PSA still going up, so on to the next thing.

[DSEE in reply to RustyDakota]

Did you finish one treatment regimen or two full treatments as I did?

It gets confusing.

Today is the 2nd treatment of the second round of taxotere-

First in 2016.

[RustyDakota in reply to DSEE]

I did 6 rounds of taxotere last year with good results. Just finished a second 6 rounds this year after discovering liver mets in January.

Results were good until it stopped working. Side effects were easier this time.

[GP24]

Another alternative for tumor in the liver is TACE:

radiologie-uni-frankfurt.de...

cancer.ca/en/cancer-informa...

[MelaniePaul]

The usual treatment with liver mets is platnium-based Chemotherapy, usually Carbo Platin. Perhaps you should discuss with your oncologist why he/she doesn't want to use this Chemo drug. The standard protocol is to go for Taxatir first because it is supposed to have fewer side-effects. But I would think that Carbo would be a better option here.

[RustyDakota in reply to MelaniePaul]

In my case, the liver biopsy showed no small-cell or neuroendocrine cells, so docetaxel was tried. Shrunk the biggest tumor from 8cm to 2cm.

Carboplatin is very likely to be in my future.

[vandy69]

I have liver and lymph node mets. Chemo has been 2 rounds (12 cycles) of Docetaxel/Carboplatin combo. That combo has reduced PSA and kept liver mets in check and mildly shrinking. After each round of chemo we rechallenged with Xtandi and the first time I got 4 months before PSA rose. This time Xtandi brought PSA down from 48 to 30 in month 1 and from 30 to 14 in month 2. Fingers crossed for continued control with Xtandi.

Best wishes. Never Give In.

Mark, Atlanta

[DSEE in reply to vandy69]

Thank you for your reply.

You do not seem to have bone Mets do you?

Your treatment plan seems to have worked well.

I am also in Atlanta and we have communicated before-

It seems this taxotere as hard as it is gives you many more years.

[vandy69]

You are correct as I do not have bone mets. Am being treated by Dr. Vasily Assikis at Piedmont Cancer Institute. This August 6th will be my 7th Anniversary with Stage 4 PCa.

Where are you being treated?

Mark

[DSEE in reply to vandy69]

Being treated at Georgia Cancer Specialists- Crane Garrott is the oncologist- but we incorporate Emory into the mix- Omar Kuchuck- for second opinions.

Dropped a bombshell on us today.

This is treatment #2 of 12.

Every 3 weeks.

[vandy69 in reply to DSEE]

What was the bombshell?

Mark

[DSEE in reply to vandy69]

The bombshell was we thought I was in 3 treatments -one treatment every three weeks and today learned it is up to 12 treatments - one every three weeks-

But whatever works!