Xgeva???: Worried about starting Xgeva... - Advanced Prostate...

Advanced Prostate Cancer

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Xgeva???

WXYZ123 profile image
14 Replies

Worried about starting Xgeva...yet another drug with scary possibilities

There are some really good bone density increasing, strengthening, calcium algae products out now, what about that instead?

Need to decide!

🙏

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WXYZ123 profile image
WXYZ123
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14 Replies
Sherpa111 profile image
Sherpa111

I went with the Xgeva. I was very hesitant like yourself as my main concern was the osteonecrosis of the jaw side effect. Get a dental work-up and make corrections to your teeth now if you decide to take the medication, and then take care of your teeth. Taking those algae calcium products will be what you do as a supplement as you’ll need to replace the serum calcium that the Xgeva draws on to strengthen your bones. I take calcium 600 MG pills twice daily along with Vit D3. Have a fatty snack or meal with those algae calcium products as it will better absorb into your body. I’ve had 5 injections of Xgeva so far and will take it for a full year. I’ve had no side effects to date and I am tolerating it well. Peace and good luck!

Kevinski65 profile image
Kevinski65 in reply to Sherpa111

There is a yearly dose of reclast. One infusion and forget about it lol.

Tall_Allen profile image
Tall_Allen

In addition to prevention of fractures and spinal compression, it also has a potential survival benefit - a possible 22% increase in survival for men with metastases, at least that's true for Zometa+Celebrex:

ascopubs.org/doi/10.1200/JC...

Of course, check calcium and Vitamin D blood levels and supplement only if necessary.

Kevinski65 profile image
Kevinski65 in reply to Tall_Allen

I can't get anyone to give me celebrex

Tall_Allen profile image
Tall_Allen in reply to Kevinski65

It's precluded for men with certain kinds of heart conditions.

Kevinski65 profile image
Kevinski65 in reply to Tall_Allen

My last group if scans talked calcium around the valves and arteries...maybe that's it.

Sherpa111 profile image
Sherpa111 in reply to Tall_Allen

Thank you.

GP24 profile image
GP24

If you are looking for an alternative to calcium algae products you can try estradiol patches to “add-back” low-dose transdermal estrogen for bone health:

prostatecancerfree.org/estr...

ncbi.nlm.nih.gov/pubmed/295...

At least fewer side effects than Xgeva and should reduce hot flushes too. A friend of mine uses these patches to help with his triple blockade (ADT3).

HOPEFULSPOUSE profile image
HOPEFULSPOUSE

My husband has been on Xgeva for close to a year - no side effects whatsoever. His MO has him taking Calcium, D3 and fish collagen (the latter apparently keeps the bones from getting brittle).

WXYZ123 profile image
WXYZ123 in reply to HOPEFULSPOUSE

Thanks! Still hoping to connect in NY sometime!

Cat&John

Magnus1964 profile image
Magnus1964

I have been getting xgeva shots for the last couple of years. On problems. Don't worry about it.

MJCA profile image
MJCA

I am on Xgeva. Yes, I have experienced some side effects. I had reservations about it as well. I have already broken and fractured bones. So, I hope it will do what it's intended for. The dental stuff DOES scare me

leo2634 profile image
leo2634

I'm Xgeva 14 months now no side effects and injection is very minor.i also had extensive dental work done while starting it no I'll effects.

Kevinski65 profile image
Kevinski65

The only side effect I got from zometa is a fluy feeling for a day and a slight temperature. As far as my teeth are concerned, I got all root canals and fillings

done beforehand. The necrosis of the jaw business I thought was kinda rare. I get a yearly dose of zometa. Denusamab or Prolia does the thing but doesn't go through the kidneys.

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