BAT - Bipolar testosterone therapy

[cesanon]

Just learned that Sartor at Tulane has 20+ patients where he is doing high testosterone to reset the prostate cancer, but doing it with just high testosterone, not the bipolar.

He thinks it's only the high level of testosterone that is doing the resetting.

[Fairwind]

Well in about a year, maybe two, we will know if he is right or not...More important than the Zytiga reset will be the cancers response to continuous high-dose testosterone..In the BAT trials, few if any of the test subjects had an explosive rise in their PSA...But this trial is not BAT. This is treating PC patients with high-dose testosterone continuously, trying to get Zytiga to work again after it has failed..Do you have a trial name or number ?

[likelylost]

My husband is a patient of Dr Sartor and has been since 2010. After the failure of xtandi, he was started on high dose testosterone with good results so far. Its been 2 months now and his psa has gone down, his liver enzymes and alk phos are now normal. Even better, he feels pretty good. Dr. Sartor is following his labs closely, and we realize that this will likely only last for a few months...at which time he will restart xtandi or zytiga, or possibly a clinical trial.

[vandy69]

I was treated by Dr. Sartor in June 2017 with high dose testosterone with daily applications of AndroGel to my upper arms. Tried to get my T to 1000 after 6 years of ADT.

Never could get T that high but after 3 months PSA rose from 4 to 18, when we stopped this "experiment". Two months later scans found numerous lesions in my liver and I immediately started chemo with Docetaxel and Carboplatin. Did this running my T up cause liver lesions---we will never know, but I have my suspicions.

Best wishes. Never Give In.

Mark, Atlanta

[Hirsch]

mark in Atlanta: your suspicions seem justified..

[cesanon in reply to Hirsch]

Mark, do you have more information on this. Enen anecdotal info.