Docetaxel side effects

[drsridhar53]

I am experiencing eye blurring 20 days after the first infusion of Doce. Is this usual, Is it reversible?

[Fairwind]

The side-effects individual patients will suffer is very hard to predict..Some guys tolerate chemo fairly well while others get slammed down hard. In my case, the third, forth and fifth day after a Dose infusion I just felt generally crappy. Then I recovered slowly, just in time for the next infusion..I'm doing Cabazitaxel (Jevtana) now, pretty much the same story. Neulasta added to prevent a complete collapse of my WBC..If we were not so desperate to live a little longer, none of us would do this...

[drsridhar53 in reply to Fairwind]

Thanks Fairwind, I agree with you that we do foolish things to extend life by a median of 4 months! That is what Doc apparently chieve with mCRPC. But to risk eyes seemed a crazy idea to me.

[Evans71720 in reply to drsridhar53]

That may be an accurate estimate if the cancer has become castration resistance. But metastasic cancer that is still dependent on the hormones the chemo can buy someone real time. +17 months average.......we have to all remain optimistic since that’s only the average. You could easily be one of the people who exceed that. So for that reason I believe the harsh Side effects could arguably be worth it for many!

Prayers for all hope you live many years!

[drsridhar53 in reply to Evans71720]

Thanks. That is very encouraging!!

[Tall_Allen]

Tell your oncologist. It may be that some neurontin is all you need.

[drsridhar53 in reply to Tall_Allen]

Thanks Tall. I am very encouraged by your reply. To take a risk with the eyes for doubtful favourable results of Doce seemed foolish to me. I shall talk to my Onc before the next round.

[Shooter1]

No vision problems till chemo cycle #7. Then loss of focus and double/triple vision. All got better after last cycle #9. For a couple of months until Xtandi side effects drug me down to an invalid. Cut dose and improved again for a while. In last 2 mo. left eye has gone from 20/30 to 20/200. Optometrist says eyes look lots better , just can't see. Meeting with retinologist next month, hope he can help, I've always had great eye sight..

[drsridhar53 in reply to Shooter1]

I am indeed sorry to hear of your problem. I do hope you regain your customary excellent vision before long. With the Beast inside us, we have only hope to live for. Thanks for you reply.

[tallguy2]

Yes, I had some blurring. My eye doctor told me that this is quite normal, as the chemo effects the amount of oil certain ducts produce that prevents the eye from drying out. I use Systane (over the counter), which helped some. But I still have some blurriness 2 months post-chemo. It is especially noticeable at night.

[drsridhar53 in reply to tallguy2]

Thanks Tallguy 2. I shall talk to my Onc before the next infusion. If this results fifteen days after the first infusion of the Hawaiian Tree bark, the prospect of five more is daunting.

[drsridhar53]

Thanks Nalakrats. I shall take the advice of my Onc before proceeding further.

[paulparry]

Usual question here. How much fluids are you taking daily?

[Hazard]

I had 9 cycles of docetaxal and fortunately no blurry vision. Lost all my hair (except pubic hair - its tough stuff down there), lost a few toenails and still experiencing peripheral neuropathy 6 months later. There are lots of side effects and we all seem to get them in different combinations. But i haven't heard about blurry vision before.

[Mattox]

I had very bad blurriness on docatacell and went to eye doctor who sent me to specialist. He said I had swelling on optic nerve but could not tell me if doc caused it. But the damage was permanent . Many weeks later right eye no better. Oncologist said he had never heard of this happening before. Who knows I had perfect vision before.

[drsridhar53 in reply to Mattox]

Hey that is frightening. I also was sent to an eye specialist yesterday (tomorrow the second Doce infusion is due). He did not find anything wrong, not even why I had vision blurring, I am sure it is part of peripheral neuropathy.

[monte1111]

Had eye tearing. Woke up a couple of times with eyes glued shut. Mostly gone now but lupron and reading Daddysdaughter post can bring a gusher. Lost both big toenails later but mostly grown back now. Fingernails had bands like a tree for each infusion. Thumbnails got really warped but are ok now. Ankle swelling that went away after chemo. Foot neuropathy after chemo--ongoing. Hot flashes mostly controlled by gabapentin. Hair mostly grown back except for mustache. It faded, doesn't grow anymore, and don't have to trim it anymore. Go figure. Other things I'm sure, including making me ramble. Good luck my friend.

[drsridhar53 in reply to monte1111]

Thanks a lot monte 1111. We deserve this for injecting a deadly poison, which the hardy goats of Mauna Kiluea and Mauna Kea avoid, directly into our blood stream.

[redbank]

I did have vision issues during the Taxotere with prednisone once I was able to stop the Prednisone my vision came back to where it was before . Chin up !!!