RP for Oligomestastasic Prostate Cancer

[Noel91]

Hi everyone!

I found this research that showed survival benefit for RP in bone-Oligomestastasic disease. I just wanted to know your opinion about it.Thank you!

insights.ovid.com/crossref?...

[Tall_Allen]

Link is blank - no abstract. I've never seen a study that shows a survival benefit for oligometastatic therapy of any kind. If you find the paper, please let me know.

[Noel91 in reply to Tall_Allen]

Hello Tall_Allen thanks for letting me know.I read it before but for some reason is not showing up anymore.I also found this one that does not actually have a big enough amount of patients but shows some evidence:

europeanurology.com/article...

[Noel91 in reply to Noel91]

Also this one:

onlinelibrary.wiley.com/doi...

I do not know if they are enough but my father had surgery and I am trying to find an explanation to that.Thank you!

[Tall_Allen in reply to Noel91]

You are confusing two different things.

The first study is about metastasis-directed therapy AFTER RP - there is NO evidence of a survival benefit:

pcnrv.blogspot.com/2017/05/...

The second study is about debulking USING RP after metastases have been discovered. which you can read about here:

pcnrv.blogspot.com/2016/08/...

The evidence is weak because of the inherent selection bias in the way they did it - those who were debulked were chosen for the therapy because their doctors thought they were better candidates. For both kinds of therapies, randomized trials are ongoing to see if they accomplish anything.

[Noel91 in reply to Tall_Allen]

Ok thats for clarifying it.May be I confused it because of the language