Acrylamide.: I wonder how many men... - Advanced Prostate...

Advanced Prostate Cancer

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Acrylamide.

pjoshea13 profile image
26 Replies

I wonder how many men skipped their morning coffee today because of the ruling by Judge Elihu M. Berle, in Los Angeles County Superior Court:

“Since defendants failed to prove that coffee confers any human health benefits, defendants have failed to satisfy their burden of proving that sound considerations of public health support an alternate risk level for acrylamide in coffee”. [1]

Acrylamide is not inherent in coffee beans - it is introduced during their roasting.

Many of us might remember acrylamide as being discovered in french fries some years back, yet fries do not come with a cancer warning, even in California.

In fact, acrylamide may be found in many cooked food subject to the Maillard reaction [2].

As an amateur cook, I'm well aware of the Maillard reaction when I bake bread or brown meat. It is something that happens to sugars (not to be confused with added sugar) when food is subjected to the proper degree of heat. It is considered to be desirable, since it does affect flavor.

But, if the Maillard reaction occurs, can acrylamide be far behind?

In 2013, there was a PCa-acrylamide paper from the Health Professionals’ Follow-up Study [3]. With 47,896 U.S. men, 5,025 cases of prostate cancer, and 642 lethal cancers, it's an important document for those concerned about acrylamide in the U.S. diet.

"Acrylamide intake ranged from a mean of 10.5 mcg/day in the lowest quintile to 40.1 mcg/day in the highest quintile; coffee and potato products were largest contributors to intake. The multivariate-adjusted relative risk of prostate cancer was 1.02 (95% confidence interval: 0.92–1.13) for the highest versus lowest quintile of acrylamide intake (p-value for trend=0.90). Results were similar when restricted to never smokers and to men who had PSA tests. There was no significant association for dietary acrylamide and risk of lethal, advanced, or high-grade disease, or for different latency periods ranging from 0–4 years to 12–16 years. We found no evidence that acrylamide intake, within the range of U.S. diets, is associated with increased risk of prostate cancer."

The authors include the usual suspects - Giovannucci & Stampfer - but the lead author was Kathryn Wilson (the acrylamide lady). Wilson has 9 papers on the subject [4].

...

It's natural to assume that acrylamide is a function of heat x time, but it occurs early in the Maillard process, so a light roast will not produce safer coffee. In fact, continued heat may help break down the acrylamide.

I used to buy coffee from a place that roasted their mail orders the day before they shipped. When the 16oz bags became 12 oz bags for the same price, I switched to local (NC) coffee - Counter Culture. The coffee is excellent but it irritates me that the local supermarkets usually show roasting dates well into the past. However, it does not seem to affect the flavor, & it turns out that acrylamide probably breaks down entirely during that period.

While acrylamide is considered to be a carcinogen in the U.S., it is not classed as such when present in food. Until Judge Berle, that is.

I wrote a review of coffee 2 years ago:

"Foods/Supplements-Vitamins: Coffee".

It's fairly clear that coffee reduces the risk of aggressive PCa, so the acrylamide is irrelevant IMO.

-Patrick

[1] nytimes.com/2018/03/30/busi...

[2] en.wikipedia.org/wiki/Maill...

[3] ncbi.nlm.nih.gov/pmc/articl...

[4] ncbi.nlm.nih.gov/pubmed/?te...

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pjoshea13
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26 Replies
Darryl profile image
DarrylPartner

Just woke from 😴 nap. Typing this while espresso machine ☕️ is warming up. Keep 😊 enjoying life.

in reply to Darryl

After injecting pure cytotoxic poison directly into my veins, I figure that a little coffee should be O.K.

JamesAtlanta profile image
JamesAtlanta

I had 2 cups of coffee today and thoroughly enjoyed them both! ☕️

James

ITCandy profile image
ITCandy

I love super strong espresso shots. All the buzz without the bathroom trips.

G9doingfine profile image
G9doingfine in reply to ITCandy

I quit smoking 20 years ago . I quit drinking 10 years ago. I quit eating red meat 2 years ago ...... can I please keep my coffee ??????

I stopped drinking sodas 2 years ago . I’ve seriously cut back on dairy . I never eat milk chocolate. CAN I please keep drinking my coffee ?????

I don’t have anything left to quit !!!!

Live long . Live strong , like a good cup of coffee !!!!

Brbnbrn profile image
Brbnbrn in reply to G9doingfine

Lol... ya know, I just realized I've cut all that stuff out bit by bit as well! Went to half-caff Folgers too... that's as far as I'm gonna go!

BigRich profile image
BigRich

I gave up coffee 4 months for another condition. Then I found out that it wasn't necessary. The latest issue is meaningless to me, for I enjoy 3 cups of coffee a day.

Rich

snoraste profile image
snoraste

You know, that’s exactly what popped into my mind after I saw he ruling: have I lost coffee?? Good post Patrick. I like my coffee.

willstain profile image
willstain

The other day they said 3 cups a day kept your arteries in good shape and warded off heart attacks, anything you cook or roast in a dry heat could give you cancer, so either let it rule your life or just live your life, either way, one day, you're gonna go pop!

Litlerny profile image
Litlerny

Happy Easter everyone! Just finished my 2nd cup of my morning coffee. I already have Stage 4 prostate cancer. I’m not worried about acrylamide. Good post Patrick.

in reply to Litlerny

I don't have to worry about "getting" cancer any more. It's great, one less thing to worry about!

Litlerny profile image
Litlerny in reply to

😎 amen to that, bro’!

TommyTV profile image
TommyTV in reply to

Takes the pressure off doesn’t it.

Tjc1 profile image
Tjc1

Remember when eggs were so bad for you? Now they are a part of a healthy diet. And everything you use has a warning from California it causes cancer.

Allthis from a state that wants to harbour criminal illegal aliens basically for a democratic vote, and give eveyone in one jurisdiction 500.00 a month for income equality!

This finding is best ignored.

Thomas

EdBar profile image
EdBar

I'm enjoying a cup while I read this...

One more cast...

Ed

craigpynn profile image
craigpynn

Coffee's on. This is much more about trial lawyers and an out-of-control California bureaucracy than it is about cancer.

in reply to craigpynn

I thought it was about activist judges who have to be ... active? On something? Anything?

larry_dammit profile image
larry_dammit

Couldn’t drink my brew when I started treatment, finally can. Nothing like sitting in the morning watching the news ,petting the dog and drinking a good cup of coffee 😜😜😜😜😜

BrianF505 profile image
BrianF505

Miss my morning coffee?! Hah, not a chance. I trade eggs from our chickens with a neighbor who does home roasting.. delish and a good deal for us both.

The only way to reduce the harmful effects of Acrylamide in coffee is to add alcohol. Distilled spirits work best: Whiskey, Rum, and Tequila are all good choices.

paulofaus profile image
paulofaus

I'm about to have my second coffee for the day - black with 1 sugar. Like the others, it's about the only pleasure I have left, I'm not gonna stop now!

in reply to paulofaus

I agree. We've already given up enough.

pjoshea13 profile image
pjoshea13 in reply to paulofaus

Paul,

Consider switching to fructose.

A teaspoon of fructose can increase the amount of hormonal vitamin D in circulation. This is important for prostate cancer cells that inhibit the conversion of calcidiol to calcitriol.

ncbi.nlm.nih.gov/pubmed/945...

Another consideration - while sucrose (half glucose + half fructose) has a moderate glycemic index of 65, fructose is only 19.

-Patrick

paulofaus profile image
paulofaus in reply to pjoshea13

Thanks as always Patrick. I already take a vitamin d3 supplement 5,000iu/day. I guess low GI is important too.

pjoshea13 profile image
pjoshea13 in reply to paulofaus

Paul,

So many men are conscientious about maintaining good D levels but fail to realize that the 25-D test measures inactive D. Ultimately, it is 1,25-D that matters. A high calcium or phosphorus intake will suppress the conversion, while fructose will increase it.

-Patrick

j-o-h-n profile image
j-o-h-n

Here's juan for you:

youtube.com/watch?v=m_INwKK...

Good Luck and Good Health.

j-o-h-n Monday 04/02/2018 11:07 PM EDT

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