Carbo Platin: Hi everyone. So Paul was... - Advanced Prostate...

Advanced Prostate Cancer

20,782 members25,890 posts

Carbo Platin

MelaniePaul profile image
20 Replies

Hi everyone.

So Paul was in hospital for a week from last Tuesday until yesterday. This was because his pain medication was changed from MST to Methadone. The first couple of days were difficult, but now he is much better and this chronic abdominal pain - which is not cancer-related - is much better.

We went to see his oncologist this afternoon to discuss the CT scan results from Monday. Unfortunately, Docetaxol (Taxatir) doesn't seem to have had any effect whatsoever on the cancer. The oncologist said that Paul's biggest problem is the liver because the cancer is growing very aggressively there and not responding to treatment. He is changing Paul to Carbo Platin now. He will have infusions every three weeks. I asked if Paul could take the combination of Docetaxol and Carbo Platin, but the doctor believes that this would be too hard on Paul's body as he was already struggling so much with Docetaxol. He also said that Carbo Platin is our last chance, as far as he can see, and that, should it not work, it would have to be palliative care only from then on.

We are heart-broken. So desperate. This really has to work now.

Written by
MelaniePaul profile image
MelaniePaul
To view profiles and participate in discussions please or .
Read more about...
20 Replies
JamesAtlanta profile image
JamesAtlanta

Our thoughts and prayers are with you and Paul...

MelaniePaul profile image
MelaniePaul in reply to JamesAtlanta

Thank you.

erjlg3 profile image
erjlg3

My heart is crying for all that you are both going through. I couldn't stop the tears from welling up in my eyes reading your pain. This has to work...

Sending hugs, love, peace and prayers Mel and Paul.

Jackie

MelaniePaul profile image
MelaniePaul in reply to erjlg3

Yes, Jackie, it really has to work!!!

Dan59 profile image
Dan59

My thoughts and prayers are with you and Paul, and that the Doctor can find something else that will work.

Dan

MelaniePaul profile image
MelaniePaul in reply to Dan59

Thanks, Dan.

MelaniePaul profile image
MelaniePaul

Thank you so much all for your prayers and good wishes.

We are hoping that treatment can start again on Monday.

And, if it is true what they have found in Germany in recent years, which is that Methadon helps with Chemo, well then we might be lucky.

Mel.

Sisira profile image
Sisira

Hope the change in chemo will bring some relief to Paul's condition.

Sending my prayers to both of you.

Sisira

MelaniePaul profile image
MelaniePaul in reply to Sisira

Thanks, Sisira.

Scruffybut1 profile image
Scruffybut1

Much love and prayers for success. Shelagh took me to St Etheldreda's on Tuesday after hospital. My favourite church. The oldest Catholic church in England. I used to go when I wrote for Universe & Catholic Times in Fleet street just for quiet prayer. Said many on Tuesday all for my friends.

MelaniePaul profile image
MelaniePaul in reply to Scruffybut1

Thanks, David, for your post.

We hope that this will be working.

MelaniePaul profile image
MelaniePaul in reply to Scruffybut1

That's lovely, David. Yes, we need to take these quiet times for prayer and good wishes. I do this a lot too for everyone here.

Nicnatno profile image
Nicnatno

Sending thoughts and prayers that it works

Nick

MelaniePaul profile image
MelaniePaul in reply to Nicnatno

Thanks, Nick.

Sorry to hear Paul is not responding to Docetaxel. Often when there is resistance to Docetaxel, the doctor will switch the patient to Cabazitaxel as a second-line Taxane. Carboplatin is often added in cases where there visceral metastases like Paul. But I can see his doctor not wanting to do that if Paul is having a really hard time with Docetaxel.

Hopefully he can tolerate the treatment of Carboplatin and it is effective against his liver mets.

Wishing you both the best and sending healing thoughts and prayers your way.

MelaniePaul profile image
MelaniePaul in reply to

Yes, Greg, that was exactly the oncologist's thinking that it would be too much for Paul to take the two.

Thank you for all your good thoughts.

MelaniePaul profile image
MelaniePaul

No, he hasn't been considered for one of those treatments. In fact, the doctors in Germany whom we asked said that LU177 is not working too well for people with as many liver mets as Paul has. I look at the blog post now.

MelaniePaul profile image
MelaniePaul

And where would yyou go to find out about gene mutation?

Betmar profile image
Betmar

My husband had extensive liver mets at diagnosis in October 2015. He was given both docetaxol and carboplatin right away for 6 infusions. This combo worked right away and he has done well since. The liver mets shrunk and have been stable since. I pray this works for Paul.

Bettie

MelaniePaul profile image
MelaniePaul in reply to Betmar

Hi Betty.

Thank you so much for your post and for your good wishes.

I just wish we could do the combination as well, but the doctor thinks it is too much for Paul's body. And he is probably right as Paul is already fighting hugely with fatigue and weakness.

I hope your husband will stay stable for a long time.

Mel.

You may also like...

Fifth Round Of Carbo Platin

again... Paul had his fifth Carbo Platin infusion on Thursday of last week. Thje oncologist says...

Husband Starting Carbo Platin Tomorrow

Hi everyone. So tomorrow Paul will have his first infusion of Carbo Platin. We have mixed feelings...

Second Round Of Carbo Platin And Good News!

everyone. So Paul had his second Carbo Platin infusion on Thursday. As you know, his first round...

Third Round Of Carbo Platin

came back from a long day in hospital about one hour ago. We are very tired. But the third Carbo...

Treatment update-continuing on Jevtana/Carbo combo

After having treatment #7, my PSA went up to 42 from 18 after #6 three weeks prior. Treatment #8...