Chemo & ADT + metformin: Hi all Spoke... - Advanced Prostate...

Advanced Prostate Cancer
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Chemo & ADT + metformin

Chubby42
Chubby42
18 Replies

Hi all

Spoke to my Oncologist the other day she is now thinking of putting me on the Chemo & ADT even tho all scans failed to show where my PC is, my PSA doubling time is 4 weeks so very aggressive which is her thinking now originally she said no as the was no evidence of bone mets which ive read gives the best results my gleeson score was 4+3.

Is there such a thing as waiting for it to reach my bones & lymph nodes before proceeding or should we just hit it with everything I can.

I have signed up for the stampede trial as well which is where the metformin comes into it plus they are just starting a new trial with ADT patches and not pills or injections.

Any thoughts welcome

Gary

18 Replies
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gusgold

Chub,

Hit it with everything...the more extensive the PCa becomes the harder it is to control

Gus

4 likes
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gregg57
gregg57
in reply to gusgold

I agree with Gusgold. I go with the Born to be Wild strategy: Fire all of your guns at once. The harder you hit in the beginning, the longer it will take to get back on its feet. Kick it while it's down and kick it hard.

3 likes
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Sisira

I am always with gusgold on this. Close your eyes and DO IT Chubby!

Sisira

1 like
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Chubby42

Thanks for the replies guy's sounds good to me.

Cheers

Gary

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Hidden
Hidden

I also agree with gusgold! Your in a war, do not take any prisoners. Go after the little devils with anything and everything. The stronger your cancer becomes, the harder the battle gets.Kill it now! Every shot you take should be a kill shot, do not give the enemy a chance to survive and attack you again.

3 likes
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gregg57
gregg57
in reply to Hidden

Agree. It's definitely a war and you have to fight it that way. The cancer never rests and will kill us if we don't fight it. It's kill or be killed. I can't see saving ammunition for later when the enemy is stronger and bigger. I'd rather use all the amo I can now. Ready, Aim, Fire!

1 like
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Dr_WHO

Be as agressive as you can! There is more and more studies that show you want to fight cancer as a street fight. You fight to win! Have you tried Axumin PET Scans? It was just approved for prostate cancer in 2016 and can find tumers a lot smaller than normal CT/PET/bone scans. It is still not widely available, but it may be worth a trip to get it done. I live in Michigan and had to go to Ohio to get my scan.

Here is a link axumin.com/

2 likes
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rococo
rococo
in reply to Dr_WHO

Where in ohio?

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Armywifedublin

Where in Ohio my husband did his radiation at the James

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Olivia007
Olivia007
in reply to Dr_WHO

Hello I’m from Michigan and my dad had the Aximum test at Troy Beaumont Hospital in March 2019 and it was inconclusive as the put it didn’t show why his PSA was rising.

Where do you live in Michigan

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Chubby42

Thanks guys ill also check Axumin scans for the UK.

Cheers

1 like
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herb1

Chubby,

Just to help you, I've been on ADT-3, intermittent, for 15 yrs. True my pca is/was only GS6. But my doubling time has been 3 months over the years...and I'm still here. One issue with your oncologist not finding a source of your cancer is that the scans may be getting done when the psa is way down; the conventional scans (CTs, bone) will not usually see anything if PSA is <1 or <2. The newer ones are better.

herb

1 like
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Chubby42
Chubby42
in reply to herb1

Wow herb1 thats amazing 15yrs

Ive been given 4 to 5yrs even if I could double mine would be great. Hope you keep on kicking it for many more years.

Gary

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j-o-h-n

Chubby42

I'll answer your question with a question. What do you do to your wife when you sit down to dinner and it's ice cold? (to the ladies in the audience it's just a joke). 😊

j-o-h-n Sunday 07/09/2017 11:56 AM EST

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Tommyj2

Noted this post from a few years back.... was intrigued at the mention of ADT patches.... what were they ( estrogen??)... did you participate in this study after all??

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Chubby42
Chubby42
in reply to Tommyj2

Hi Tommy, I'm in the UK stampede trial Arm K which is early chemo, Hermone & Metformin, I didn't get the hormone patches ;-( shame but thats life when your on trials.

Cheers

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Tommyj2
Tommyj2
in reply to Chubby42

I'll tell you .... the general public should spend some time on this forum and SEE how damnably unpredictable this disease can be..... who would have figured that your G7 cancer would have given you THIS kind of trouble and required such extensive treatment.... what possessed you to get it Biopsied at a 3 ? ( though lucky that you did as I suspect it might well have jumped to a much higher G level in short order...

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Chubby42
Chubby42
in reply to Tommyj2

I had a lump on the side of my prostate plus a scan showed something.

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