Chemo & ADT + metformin: Hi all Spoke... - Advanced Prostate...

Advanced Prostate Cancer

22,372 members28,135 posts

Chemo & ADT + metformin

Chubby42 profile image
18 Replies

Hi all

Spoke to my Oncologist the other day she is now thinking of putting me on the Chemo & ADT even tho all scans failed to show where my PC is, my PSA doubling time is 4 weeks so very aggressive which is her thinking now originally she said no as the was no evidence of bone mets which ive read gives the best results my gleeson score was 4+3.

Is there such a thing as waiting for it to reach my bones & lymph nodes before proceeding or should we just hit it with everything I can.

I have signed up for the stampede trial as well which is where the metformin comes into it plus they are just starting a new trial with ADT patches and not pills or injections.

Any thoughts welcome

Gary

Written by
Chubby42 profile image
Chubby42
To view profiles and participate in discussions please or .
Read more about...
18 Replies
gusgold profile image
gusgold

Chub,

Hit it with everything...the more extensive the PCa becomes the harder it is to control

Gus

in reply togusgold

I agree with Gusgold. I go with the Born to be Wild strategy: Fire all of your guns at once. The harder you hit in the beginning, the longer it will take to get back on its feet. Kick it while it's down and kick it hard.

Sisira profile image
Sisira

I am always with gusgold on this. Close your eyes and DO IT Chubby!

Sisira

Chubby42 profile image
Chubby42

Thanks for the replies guy's sounds good to me.

Cheers

Gary

I also agree with gusgold! Your in a war, do not take any prisoners. Go after the little devils with anything and everything. The stronger your cancer becomes, the harder the battle gets.Kill it now! Every shot you take should be a kill shot, do not give the enemy a chance to survive and attack you again.

in reply to

Agree. It's definitely a war and you have to fight it that way. The cancer never rests and will kill us if we don't fight it. It's kill or be killed. I can't see saving ammunition for later when the enemy is stronger and bigger. I'd rather use all the amo I can now. Ready, Aim, Fire!

Dr_WHO profile image
Dr_WHO

Be as agressive as you can! There is more and more studies that show you want to fight cancer as a street fight. You fight to win! Have you tried Axumin PET Scans? It was just approved for prostate cancer in 2016 and can find tumers a lot smaller than normal CT/PET/bone scans. It is still not widely available, but it may be worth a trip to get it done. I live in Michigan and had to go to Ohio to get my scan.

Here is a link axumin.com/

rococo profile image
rococo in reply toDr_WHO

Where in ohio?

Armywifedublin profile image
Armywifedublin in reply toDr_WHO

Where in Ohio my husband did his radiation at the James

Olivia007 profile image
Olivia007 in reply toDr_WHO

Hello I’m from Michigan and my dad had the Aximum test at Troy Beaumont Hospital in March 2019 and it was inconclusive as the put it didn’t show why his PSA was rising.

Where do you live in Michigan

Chubby42 profile image
Chubby42

Thanks guys ill also check Axumin scans for the UK.

Cheers

herb1 profile image
herb1

Chubby,

Just to help you, I've been on ADT-3, intermittent, for 15 yrs. True my pca is/was only GS6. But my doubling time has been 3 months over the years...and I'm still here. One issue with your oncologist not finding a source of your cancer is that the scans may be getting done when the psa is way down; the conventional scans (CTs, bone) will not usually see anything if PSA is <1 or <2. The newer ones are better.

herb

Chubby42 profile image
Chubby42 in reply toherb1

Wow herb1 thats amazing 15yrs

Ive been given 4 to 5yrs even if I could double mine would be great. Hope you keep on kicking it for many more years.

Gary

j-o-h-n profile image
j-o-h-n

Chubby42

I'll answer your question with a question. What do you do to your wife when you sit down to dinner and it's ice cold? (to the ladies in the audience it's just a joke). 😊

j-o-h-n Sunday 07/09/2017 11:56 AM EST

Tommyj2 profile image
Tommyj2

Noted this post from a few years back.... was intrigued at the mention of ADT patches.... what were they ( estrogen??)... did you participate in this study after all??

Chubby42 profile image
Chubby42 in reply toTommyj2

Hi Tommy, I'm in the UK stampede trial Arm K which is early chemo, Hermone & Metformin, I didn't get the hormone patches ;-( shame but thats life when your on trials.

Cheers

Tommyj2 profile image
Tommyj2 in reply toChubby42

I'll tell you .... the general public should spend some time on this forum and SEE how damnably unpredictable this disease can be..... who would have figured that your G7 cancer would have given you THIS kind of trouble and required such extensive treatment.... what possessed you to get it Biopsied at a 3 ? ( though lucky that you did as I suspect it might well have jumped to a much higher G level in short order...

Chubby42 profile image
Chubby42 in reply toTommyj2

I had a lump on the side of my prostate plus a scan showed something.

Not what you're looking for?

You may also like...

ADT + Chemo vs ADT followed by Chemo

EDIT: Please read the replies to my posting below. After I posted it some other members posted...
AlanMeyer profile image

Metformin + ADT

-Patrick...
pjoshea13 profile image

Chemo & ADT slow

Hi all just checking on other people's experience with Chemo & ADT treatment. Before starting my...
Chubby42 profile image

intermittent ADT+Abiraterone

Six months ago I ended a 12 month holiday from my ADT + abiraterone. (In this post, I’m not asking...
Catskills profile image

Lifelong ADT vs Adjuvant ADT and other questions

I'm confused regarding Lifelong ADT vs. Adjuvant ADT, what my options are. Recently at the Mayo -...
swwags profile image

Moderation team

Bethishere profile image
BethishereAdministrator
Number6 profile image
Number6Administrator
Darryl profile image
DarrylPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.