Clinical Trials

[Blair77]

Hi,

I'm wondering how many people are participating in clinical trials?

Thanks,

Blair

[AlanMeyer]

I was in a radiation clinical trial and a couple of subsidiary trials (tissue testing) at the U.S. National Cancer Institute. I thought it was very worth while. Benefits to me were:

- Access to excellent doctors.

- Comprehensive medical testing and scanning.

- Free treatment (not even a copay or a parking lot fee).

- Free followup for about six years.

- Extra followup (monthly PSA testing) when PSA bounced around.

- The treatment worked!

Some articles were published about the treatment. I hope they offered some benefit to cancer research.

Alan

[Gecrellin]

I participated in one briefly using sirolimus in conjunction with docetaxel and Carboplatin, but was pulled when the cancer spread to my liver. Right now I am on bipolar androgen therapy, but outside a trial even though the treatment is still experimental. Looking at others when this treatment stops working.

[CBurnett in reply to Gecrellin]

May I ask how you r getting BAT without being in a trial??

[Gecrellin in reply to CBurnett]

There is a trial going on at my clinic too, but I didn't qualify since I have had both Zytiga and Xtandi. It is simply off label for the testosterone.

[jal1954]

I'm in a trial at MD Anderson for nanoparticles of Taxotere. Too early for any results.

[TommyTV]

I'm on Stampede in the UK. On Aberaterone plus Zoladex plus Prednisone.

5.5 years so far. PSA at start 600+, Gleason 7. PSA currently 0.1.

Very happy!

[bb66hotflash]

I have been in three drug trials. First one with Galeterone, was stopped after 31 days due to uticaria (rash from head to toe). 2nd one was on Enzatulimide for 31 months, until fatigue became debilitating. 3rd one was a Level 1 on AZ-8146, had to stop after liver enzymes (ALT and AST) rose rapidly. Did a retry on half dose and had same result. Overall a lot of good and some not so good.

[bb66hotflash in reply to bb66hotflash]

Correction AZD8186

[Pguenette]

I'm on one via Johns Hopkins Baltimore/DC. It's for double continuous ADT. I'm fortunate to be in the trial arm doing Eligard (3-month shot) with Abiterone (daily pill). Other arm substitutes something else for the Abiterone and having harsher side effects. I had Gleason 10, failed surgery and radiation. Thus far on this trial 27 months undetectable PSA.

[Belinda4444 in reply to Pguenette]

What is the name of this trial.

What doctor is leading this trial.

We are on a trial at Johns Hopkins now, Ken Pienta is our doctor.

[Pguenette in reply to Belinda4444]

Trial through Johns Hopkins is national in scope and is led by Dr. Channing Paller.

[Hidden]

My experience was one of ignorance. I was on one for non-met PCa. After about a year an F-18 pet showed I had mets in spine, hip and sacrum. The study 'docs' insisted I didn't have mets, after viewing the same images. I was stupified. I left the trial, and never heard another word from them. I have my contract that provided years of follow up care no matter how you left the study. I was, to say the least, disappointed.

Joe

[ctarleton]

As my cancer was becoming castrate resistant after initial ADT, I was offered a clinical trial involving Yervoy (ipilimumab). After taking into consideration other health issues I was having at the time, plus some reports of earlier clinical trials adverse effects involving this agent, I decided to decline the offer for the short term.

Charles