Santa Claus Offers Protocol To Slow P... - Advanced Prostate...
Santa Claus Offers Protocol To Slow PCa Growth
Gus,
I was using Metformin for a number of years before the Swiss study came out. Suddenly, Myers was its greatest fan.
As a person with a disease for which there is no cure, I feel that it is worth the risk to begin using something for which there is mounting evidence of benefit. But it would be reckless of Myers to jump the gun. Some of us can't afford to wait for the definitive study.
I was therefore also ahead of him with statins. & I note that he still only uses them on men who are unable to lower LDL-C sufficiently. Who knows, he may use them more broadly in the future (when the next Swiss paper comes out. LOL)
What I like about Myers, is that a close listen to all of his vblog posts provide a basic road map for what we can do ourselves. We can probably improve on it, but we are fortunate to have it.
I post PCa research on supplements. Dr Myers would no doubt dismiss most of the studies. Doubtless he rejected many studies before embracing vitamin D & resveratrol, e.g. It's worth noting - for those who take no supplements - that Dr Myers does recommend some.
Oddly, there is one area where he did jump the gun. Disturbed by the frequency of cardiovascular risk in new patients, he began to recommend a Mediterranean diet. He had no way of knowing how that might affect PCa progression. e.g. it is fairly high in fat.
I see PCa as largely being a metabolic disease. In fact, it could be added to the list of indicators of the metabolic syndrome. By tackling MetS via the Med. diet, he is helping to slow progression, IMO.
Anything that can increase PSADT is useful.
-Patrick
Patrick,
Does Meyers still recommend Lycopene?
Rich
Rich,
I don't recall hearing that he ever did.
As of now, a PubMed search on <prostate lycopene> returns 439 hits. Something tells me that there must be something to it.
Myers discounts epidemiological studies because they can't determine cause. They are good for hypotheses, but you need a "real" study to prove a hypothesis. & Dr Myers is picky.
-Patrick
Pat,
I thought the story on lycopene was that it may be of some help if tomatoes are taken in an oil base, such as an olive oiled salad, rather than, e.g., as a raw tomato or a lycopene pill with a glass of water.
herb
Herb,
Yes - all carotenes need to be taken with fat.
But in addition, the tomatoes must be cooked, to alter the lycopene into its "cis" form.
-Patrick
Patrick,
I'm glad you brought that up. I'm a chemist and do know what you mean. A few months ago I was looking up bicalutamide half life and came across a comment that the R-isomer was the active one and the only one absorbed (90%). (I'm working from memory). I didn't know bicalutamide had R and S isomers. Now I'm concerned that the generic products we are being sold may have different ratios and could have different effectiveness. I did experience this with a antidepressant years ago. The racemic mix generic was ineffective.
Herb s
Patrick,
Meyers in his book "Beating Prostate Cancer" recomends it; however, the book copyright date is 2007.
Rich
Rich,
I have found an account of a talk he gave in 2006. Here's the part that mentions lycopene:
"To support the arguments in favor of tomatoes in the Med diet, he cited again the Harvard Study of 1,202 men who had been treated for PCa with surgery and/or radiation. Those in the group who had consumed the largest amounts of tomatoes had a “44% reduction in recurrence” when compared to the lowest consuming group.
"He cited another small study, Ansari et. al. BJU 92, 375, 2002. In this study, 54 pts with metastatic disease underwent orchiectomies with the group stratified into with and without lycopene in their pre-orchiectomy diets. A “complete psa response” was found in 78% of those taking the lycopene vs. 40% complete response in the control cohort. Bone scans were 15% vis 30% with and without lycopene.
"Deaths occurred in 13% with lycopene diets vs 22% w/o. This was a very small sample so its statistical significance is probably limited.
"Myers cited another small study of 26 men newly diagnosed. The study separated the men into two groups: placebo vs 15 mg of lycopene twice daily for three weeks prior to radical surgery. Kucuk, et. al reported that in this study, 73% of the men on lycopene had cancer free surgical margins vs 18% in the control group. (Kucuk, et.al Cancer Epidemiology Biomarkers 10, 861, 2001)."
Seems uncharacteristic of Myers to recommend lycopene based on such thin stuff. Perhaps he likes tomatoes.
Elsewhere:
"Dr. Strum suggests 15 mg taken twice a day, Dr. Myers suggests 10mg three times a day."
Strange, though - I don't remember any of his patients mentioning lycopene.
& lycopene does have its detractors.
-Patrick
Thanks for posting that video. I'll bet most urologists would scoff at some of his recommendations.
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