Hi there! I'm new here. I have severe allergic asthma. I take Symbicort, Spiriva, Zyrtec, and Flonase daily. I just started Xolair (Omalizumab) but I'm already worried it might not be a good fit. I feel exhausted, have had insomnia for days (I hadn't realized histamines play such an important role in regulating the sleep cycle), and generally don't feel like myself. I'm going to give it a few more weeks but if I don't improve I'm not sure I'll keep going.
My last pulmonologist had wanted to start me on Nucala (Mepolizumab) even though my Eosinophil count isn't that high (200). I'm wondering if that may be a better fit for me since I'm thinking IL-5 (which it suppresses) probably plays less of a role in regulating the body's rhythm than histamines do.
Does anyone on here have experience switching from Xolair to Nucala or vice versa?
Thanks so much in advance for any insight you may have!!
