I take 4 grains Efra and 20mg T3. This has got me up on my feet! hooray one would think but no - I saw a horrid female Endo at Gearge Elliot hospital reputed to be at cutting edge for people with ME/Fibromyalgia. She said heart rate dangerous and wants reduce meds to 10mg T3 ONLY. Can anyone comment on 127 heart rate. Also when I reduced meds ended up back in bed!!!! So f..... The risks. I'm not looking for longevity but Quality if life.