Low cholesterol levels are good markers for central hypothyroidism in case with dialysis using roxadustat

[helvella]

Roxadustat is used for treating renal anaemia. I know nothing about it beyond this paper.

But in case anyone is using it, this seems to be a potentially important impact.

A simple case report. And an issue which is worth trying to remember for regular contributors! Even if it is rare.

Low cholesterol levels are good markers for central hypothyroidism in case with dialysis using roxadustat.

Abstract

Recently, hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitors have been used for renal anemia, but side effects have also been reported. We report on the association of central hypothyroidism and cholesterol with roxadustat. Based on this case and previous reports, we believe that patients receiving roxadustat should have their thyroid function and cholesterol levels checked regularly.

Full paper open access here:

europepmc.org/article/MED/3...

[Regenallotment Ambassador]

well would you look at that graph 👀

If ever there was proof that thyroid replacement has a relationship with cholesterol… bingo! 📈📊📉

[helvella Administrator in reply to Regenallotment]

Quite!!