Why did I go looking... Zinc inhibits cortisol - Thyroid UK

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Why did I go looking... Zinc inhibits cortisol

TiggerMe profile image
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47 Replies

pubmed.ncbi.nlm.nih.gov/170...

So I need to add that into the supplement timing game... not much good taking it at the same time as Hydrocortisone or Adrenal Glandular 😮

medericenter.org/resources/...

Might be handy for anyone with high cortisol to help bring it down though...

So ideally zinc in the evening with magnesium as they benefit each other... synergistic apparently

My cortisol is low throughout but if it's going to take a hit then I guess evening is best for me

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47 Replies
greygoose profile image
greygoose

I read that you should never take zinc and magnesium together.

TiggerMe profile image
TiggerMeAmbassador in reply togreygoose

I read that too but it is linked to an abnormally high intake of zinc 142mg... why anyone would be taking this amount 🤷‍♀️

They suggest RDD 270mg magnesium and 7mg zinc for females 19 -75+

HealthStarDust profile image
HealthStarDust in reply toTiggerMe

I’ve been having mine together, and I think it’s OK fingers crossed 🤞🏽

TiggerMe profile image
TiggerMeAmbassador in reply toHealthStarDust

At least if I take it in the evening it is definitely away from wholegrains, hc and levo... I'll give it a go 🤗

HealthStarDust profile image
HealthStarDust in reply toTiggerMe

I have mine in the evening. As we knows, what works for some people, doesn’t for others. So some people probably do well with zinc and magnesium combined, while others may not.

I hate to assume everything we know is not subject to variation or change. But, that’s just me.

Good luck. Hope it works out for you!

greygoose profile image
greygoose in reply toTiggerMe

Hmmm... I don't know then.

TiggerMe profile image
TiggerMeAmbassador in reply togreygoose

Perhaps I should just add ionic zinc to the epsom salts and soak it all up in the bath🛀 lovely!

greygoose profile image
greygoose in reply toTiggerMe

I don't know if that would work.

TiggerMe profile image
TiggerMeAmbassador

Sneedle Regenallotment Delgor Alanna012 Leaney janeroar Jaydee1507 radd ... who else have we been talking zinc with?

Alanna012 profile image
Alanna012

Ooo thanks for this nugget Eeyore, I'll add the magnesium to my zinc then.

Blissful profile image
Blissful

So ideally zinc in the evening with magnesium as they benefit each other... synergistic apparently

That's what I do - I've been using Dr Mercola's Magnesium L-Threonate . It is a bit pricey (as is anything post Brexit coming from the US). It is said to be able to cross the blood/brain barrier. My observation is of course totally subjective but I feel my brain likes it :)

I think everything works best when the relationship is symbiotic (meaning mutually beneficial -v- parasitic). Everything needs co-factors - zinc and mag need (balanced) calcium etc. Enzymes need co-factors.

grassrootshealth.net/blog/u...

I used Ionic zinc about 20 years ago - it was this one:

metabolics.com/ionic-zinc.html

I also took ionic mag at the same time - I felt the benefit.

TiggerMe profile image
TiggerMeAmbassador in reply toBlissful

I liked the sound of L-Threonate too... I tend to buy a complex to cover more bases 🤷‍♀️ so this one also has glycinate and taurate and then there's epsom salt baths

Thanks for the links, I'm just waiting for OAT results so then I'll be rejigging again I expect 🤗

Gradually getting everything back to a good place

Jaydee1507 profile image
Jaydee1507Administrator in reply toTiggerMe

Just wondering did you do the OAT yourself or with a practitioner of some sort?

Are you aware that low zonc makes histamine intolerance worse? healinghistamine.com/blog/z...

TiggerMe profile image
TiggerMeAmbassador in reply toJaydee1507

I've done it myself, with the thought of involving a practitioner once I've seen the results...

Yes I found that link last week 😕 and posted it up, funny that GP's aren't interested in Zinc as it is another little thing with big repercussions

I might call it zonc from now on 🤣

Jaydee1507 profile image
Jaydee1507Administrator in reply toTiggerMe

They just don't do details like zinc. I know its very important to many people but at the end of the day they are general practitioners, jack of all trades and masters of none.

Hopefully raising your level will really give you some more progress and good job you got it tested.

waveylines profile image
waveylines in reply toJaydee1507

I actuary don't think they are Jack of all trades anymore. Their basic medical ignorance is truly scary. And I'm tired of having to reverse the roles and train them up.... cos what happens if I don't know? Well I know what happens it gets left....until you research it yourself.

Quite like a GP who knows their oats for a change. What a blessing that would be.... I can dream.... Lol...

HealthStarDust profile image
HealthStarDust in reply towaveylines

I agree with you. Many need us as educators as they seem to have lost all clinical judgement and rely on NICE Guidelines and questionaries!

There are a few good ones popping around but hard to find. But, yes, overall Jack of No Trades and hate us for using ‘Doctor Google’, which is simply inconsistent with what’s being touted as ‘self directed care’. I feel more sorry for those who are not accustomed to self directed care. Still, it shouldn’t be this way. We should be able to trust we are dealing with someone competent to manage our health.

waveylines profile image
waveylines in reply toHealthStarDust

I just tried to book a GP appointment having waited in the queue on the phone. I was greeted with a triage form to fill in which Doctor would decide what to do in a few days time. The form start off with if you have dizzyness, chest pain or temperature please go to a&e. (no wonder a&e are overwhelmed!) After filling the form in it then requires me to tick a box effectively with me accepting responsibility if anything is missed because I filled the form in! I just despair....

I did say to the receptionist that it was just another barrier being put up and what if you are not IT friendly or illiterate or blind or severely disabled.

It's not medical care....

HealthStarDust profile image
HealthStarDust in reply towaveylines

Yep. It’s pretty p€€s poor. Sadly, I’ve been at surgeries where this was the case before lockdowns innovations where you’d show up for the same day appointment clinic, fill in a form and then you’re prioritised according to need.

I soon learned to write very little on the form with mixed results, just for my own privacy really and I know my health is too ‘complex’ for an admin type to make a decision on my priority.

radd profile image
radd in reply toTiggerMe

Eeyore,

The OAT can be tricky to interpret as one high or low result doesn't make a conclusion but certain combinations can. This site is trying to get you to use their interpretation service but they also supply a list of all that is been tested and what results can mean.

Enjoy. You'll be there for hours 😬 .. healthmatters.io/biomarker-...

TiggerMe profile image
TiggerMeAmbassador in reply toradd

Thanks Radd... Ahead of you there! I was up till 2am having spent 4 hours going through using this site last night... drjockers.com/organic-acids... Looks much the same but has a good tutorial video

They do actually give you some feedback with the results, but my word you need several functioning brain cells at the same time to get through it all!!

Have we discussed dairy intolerance and calcium intake??

Hedgeree profile image
Hedgeree in reply toTiggerMe

Hi Eeyore,

What are OAT results?

TiggerMe profile image
TiggerMeAmbassador in reply toHedgeree

Organic acid test... they test your pee 🤷‍♀️

and give very complicated answers that I may or may not understand 🤣

so will likely need to see a naturopath or functional to decipher

waveylines profile image
waveylines in reply toTiggerMe

Eeyore I love your style! 😍You will win in the end for sure.... Xx

Hedgeree profile image
Hedgeree in reply toTiggerMe

Ah ok 😊

I really enjoy reading your posts as I learn a lot from them and the replies you get ☺️

TiggerMe profile image
TiggerMeAmbassador in reply toHedgeree

Me too … the replies are priceless 🤗

It’s like a Guinea pigs convention 😁

Hedgeree profile image
Hedgeree in reply toTiggerMe

☺️🤣

Sneedle profile image
Sneedle

Did we talk zinc? Or zonc?Would like to help but I can't remember...🤔

I think a functional practitioner sounds like a good idea for your organic wee interpretation.

As they can look at your zonc as well, within your whole picture.

Or a functional doctor... now that would be a thing😁

TiggerMe profile image
TiggerMeAmbassador in reply toSneedle

Oxymoron... just sprang into my head 😆

You were there at one point winding radd up and I got the blame... thought I'd tag you in 😉

Sneedle profile image
Sneedle in reply toTiggerMe

😂 excellent

Ha! Nice revenge 😄

TiggerMe profile image
TiggerMeAmbassador in reply toSneedle

It's all good brain exercise trying to work out what, when , why... recall 😵‍💫

radd profile image
radd in reply toTiggerMe

Eeyore,

I haven’t read your links and think you are reading everything too literally, eg these are only two papers within the many thousands 😁.

'Zonc' may inhibit cortisol secretion but as I understand it only temporarily. It is involved in numerous enzymic reactions, and like cortisol essential for immunity (especially SOD - major class of antioxidant enzyme) and over time will help stabilise hormones and proteins when optimised.

We tend to think of only adaptogens helping to normalise cortisol levels but many nutrients/vits will exert this effect also when optimised and utilised correctly by the body by encouraging cortisol higher or lower.

'Zonc' deficiencies should always be addressed. Yes, take it with magnesium. I always do within a mutlivit. Once deficiencies are addressed I think it wrong, expensive and inconvenient to keeping taking high doses of individual supplements when a general all-rounder covers all bases.

For every paper you read results of 'xxx', when anothers conclusion will be the exact opposite! And after all, we do not separate out our foods/meals to achieve optimal nutrient retrieval.

I have advocated for multivits on the forum for some time. The incorrect assumption they are of little use is only directed towards people with ongoing large deficiencies, or the cheaper branded supplements that risk using inferior ingredients and often in the wrong ratios just to save money. Brands such as Thorne, Seeking Health, etc do not do this, and will offer many forms of combos to suit all.

Love the new renaming of 'zonc'. When we're all zinc'd up we can say we're all zonc'd out! 🤣

TiggerMe profile image
TiggerMeAmbassador in reply toradd

Thanks, oh wise one 🤗

It was just really to get the timings right whilst dealing with the initial deficiency and also the fact that my cortisol is already very low.... just did a cortisol saliva test to see what effect a single 5mg of hc was having and it turns out to be very little but then I saw this connection and of course I had taken my 30mg Zonc around the same time.... so I'm none the wiser.... always the way when testing!

Zonc has now joined Mag in the evening and hopefully I'll be totally zonc'd out sooner rather than later 😊

janeroar profile image
janeroar in reply toradd

Interesting. Out of interest radd which multi do you take? I agree it’s bl**dy expensive taking individual ones but finding a multi that’s right for me hasn’t been easy.

radd profile image
radd in reply tojaneroar

janeroar,

I like Seeking Health as they offer a very large variety concerning the different forms of folate and Vit B12 and the supporting enzymes ( I need unmethylated B12 but can take folate ok). They also offer alternatives for other different needs such as a multivitamin minus copper (when someone is low in zinc) or another that includes liver and antioxidant support.

I just got fed up taking copious amounts of pills and these suit my needs well. However, I'm now detoxing mould so taking a few more pills in the forms of binders and probiotics, etc 🙄.

janeroar profile image
janeroar in reply toradd

thanks radd going to check them out!

TiggerMe profile image
TiggerMeAmbassador in reply toSneedle

I like Zonc better 😏

helen_m profile image
helen_m

Years ago, I tried zinc and magnesium together in the evening and found they cancelled each other out.

I'll try zinc, can no longer take magnesium 😱due to kidney injury.

Helen

HotelHurricaine profile image
HotelHurricaine

Thanks for this TiggerMe

For anyone interested, I have just had my zinc tested by my GP - I found a tip on here that someone had called GP and said their dentist had requested they had a zinc test (fib) and it worked for me too!

Sneedle profile image
Sneedle in reply toHotelHurricaine

Needs must!

TiggerMe profile image
TiggerMeAmbassador in reply toHotelHurricaine

Welcome to the 'fib' club 🤗pass it on 😉

Delgor profile image
Delgor

I've actually been taking my zinc together with vitamin c in the afternoon (I just have to be different - lol). Keep up the good research work and you will be promoted to Prof Eeyore😁

TiggerMe profile image
TiggerMeAmbassador in reply toDelgor

It's a strictly one piece of information in... and one out system I run on 🫠

TiggerMe profile image
TiggerMeAmbassador in reply toDelgor

You're ahead of the game!!

Delgor profile image
Delgor in reply toTiggerMe

Dashed out to have a walk in between showers - zinc hasn't made any difference as yet but it's still early days so I keep hoping🤗

Imaaan profile image
Imaaan

Merci madame

Regenallotment profile image
RegenallotmentAmbassador

for the purposes of Guinea pig experimental balance I’ll carry on with zinc in the morning with the Bs and report back after next test. If no improvement I’ll switch to with mag. 👍

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