Stopped taking propanolol effect on thyroid hormones?

[lisan1]

Hi,

I have been taking propanolol 10mg X 3 times a day for my pots. I have now stopped taking it. Would it affect my thyroid hormones? Am taking both levothyroxine and liothyronine.

[PurpleNails Administrator]

Propranolol is said to reduce FT4:FT3.

As you control the T3 it might not have a significant affect.

I found my FT3 increased disproportionately after I stopped. Although I have hyper (on carbimazole) & was on 40mgx3 propranolol dose.

Shouldn’t be stopped one 1 go, it’s best to reduce slowly. I had migraines and GP put me back on propranolol to prevent them.

Got down to low dose for a long time, but have had it increased recently.

[lisan1 in reply to PurpleNails]

Thank you! What dose did you go from and to what dose? Do you know your levels before and after stopping.

[PurpleNails Administrator in reply to lisan1]

I’d been on 20mg carbimazole & 40mg x3 propranolol for about 2 months my results at first endocrinologist clinic were

TSH <0.01

FT4 38%

FT3 50%

The carbimazole was halved to 10mg and propranolol stopped by specialist

Next test bout 7 weeks later

March 2019

TSH <0.01

FT4 69.23%

FT3 113.64% over range

So FT4 didn’t quite double but FT3 rose more than double.

Was unwell with migraines until GP put me back on propranolol. Slowly reduced it. I think I did about 30mg a week eg 10mg less on 3 of the days.

Got down to 20mg on some days, but I had to take pills on time. Couldn’t take a tablet late or I found I needed extra.

[lisan1 in reply to PurpleNails]

Thanks!

[SlowDragon Administrator]

Yes it will

It’s slows uptake and conversion rate of Ft4 to Ft3

It’s extremely important to reduce propranolol very slowly usually over several months

Personally I took 4-6 months to ween slowly off 4 x 10mg

More on my profile

Propranolol and thyroid

pubmed.ncbi.nlm.nih.gov/168...

rejuvagencenter.com/hypothy...

labtestsonline.org.uk/tests...

Drugs that may decrease PTH include cimetidine and propranolol.

[lisan1 in reply to SlowDragon]

Thanks. I have already stopped Propranolol. Did your results change? Do you know what they were before and after propranolol?

[SlowDragon Administrator in reply to lisan1]

sorry no

Going gluten free enabled me to slowly stop propranolol

T3 added on NHS prescription 6-9 months after