still can’t increase to 5mcg T3: hey everyone... - Thyroid UK

Thyroid UK

141,182 members166,423 posts

still can’t increase to 5mcg T3

Thyroid_mum profile image
19 Replies

hey everyone,

Been treating adrenals for a few weeks and been on 2.5mcg T3 twice a day for 14 days with 100/125 Levo.

Tried to increase my morning T3 dose yesterday and had anxiety and palpitations 😣.

Any other suggestions on how to tolerate higher dose of t3? I’m thinking of taking 2.5mcg 3 or 4 times a day if I can’t get to tolerate 5mcg in a single dose.

Written by
Thyroid_mum profile image
Thyroid_mum
To view profiles and participate in discussions please or .
Read more about...
19 Replies
SlowDragon profile image
SlowDragonAdministrator

yes try adding 3rd dose of 2.5mcg

And ….if necessary a 4th

Then wait 6-8 weeks before trying to take 5mcg in morning

Thyroid_mum profile image
Thyroid_mum in reply toSlowDragon

what time between do you recommend?

SlowDragon profile image
SlowDragonAdministrator in reply toThyroid_mum

If 3 doses …..roughly equal 8 hour intervals

Waking, mid afternoon and bedtime

Or if T3 at bedtime keeps you awake initially

Waking early afternoon and 6-7pm

Many, many members find small dose at bedtime improves sleep

If you need to go to 4 doses in 6-8 weeks…..every 6 hours approx

Thyroid_mum profile image
Thyroid_mum in reply toSlowDragon

thank you 🙏🏼

McPammy profile image
McPammy

Try splitting your levothyroxine dose also. I find splitting levo and T3 doses really helped me. Take half your levo dose when waking and the 2nd half going to bed as well as splitting your T3 8hrs apart.

AS14 profile image
AS14

Check your serum iron if thats below optimal it can cause the same issues raising T3 as cortisol problems can.

Ferritin is important but in tolerating T3 serum iron is crucial. I believe serum iron needs to be 55 -70% through range.

I dont have the full iron panel details to hand but Im sure if you ask someone will help.

This information can be found on Stop the thyroid madness and Paul Robinsons book recovery with T3, and Im pretty sure you can find it on his website too. Sorry cant remember the exact name of site its easy to find though.

Thyroid_mum profile image
Thyroid_mum in reply toAS14

my ferritin was 122 with the range 30-150 in my last blood test in early June

Thyroid_mum profile image
Thyroid_mum in reply toThyroid_mum

will have to order and iron test

AS14 profile image
AS14

I missed serum iron for a very long time, I thought my intolerance of T3 was just down to my very low cortisol.

I saw a post on stop the thyroid madness about not tolerating T3 but not everyone agrees with STTM so to be sure I I bought Paul Robinsons book and he talks about everything needed for T3 and he talks about it there,in far more detail. Very clever man highly recommend his book Recovery with T3.

I fixed my low cortisol by taking small amount of ndt as in his ct3m protocol and in a few weeks I had almost perfect cortisol, quite miraculous given my cortisol was practically flat lined.

I still couldnt get ndt to work so knew I was missing something and long story short it was serum iron. Soon as that was right I could handle my ndt abd started feeling much better.

Unfortunately a non thyroid health issue came up and I lost my good cortisol and iron and I crashed again but thankfully Im almost back to where I need to be with them, few weeks and I should be able to start again.

Important to know that you also need good levels of vitamin B1 to handle T3, gives you awful heart symptoms if you are deficient in it.

Its frequently said on this forum how important nutrients are and I can say its absolutely true.

Thyroid_mum profile image
Thyroid_mum in reply toAS14

thank you - i will ask my GP to check iron serum and vitamin B panel - hopefully it can be done on the NHS. My issue is high cortisol and low DHEA - so I have adrenal supplements and DHEA - was really hoping that would have fixed the issue not tolerating T3. But now since starting the DHEA I am having irregular periods (every 2 weeks) and have an awful metallic taste in my mouth which I've read and been advised is hormones (estrogen) fluctuations. Just can't win eh? 🙈

AS14 profile image
AS14

Im sorry I dont know anything about DHEA but I know too much estrogen stops thyroid hormone working. I believe the term is estrogen dominance, Im sure there will be people on here who can advise. Im on hrt and if I use it more than five days a week it stops thyroid function, its happened a couple of times.

I had very low morning and lunch time cortisol and high cortisol around dinner time and took either holy basil or zinc( tiny amount) for the high and either worked. Small amount of ndt two hours before getting up fixed my very low early morning cortisol and lunch time to practically perfect.

I highly doubt gp will do full iron panel or test b panel, possibly b12 but not the full panel plus vitamin b1 is almost impossible to test, it needs a very specific and very expensive test . There is a Vitamin b 1 test on the nhs but its extremely unreliable, however there is a very accurate test but its not available on the nhs and its hard to find even a private doctor to test it and its extremely expensive.

Most b vitamins dont stay in your body long apart from b12, so its simple and safe to take b vitamins everyday just to make sure youve got everything covered, Im sure if you ask someone will recommend a good supplement.

I take B minus from seeking health it does not contain folate or b 12 and only has relatively small amounts of vitamin b1. I take a bigger dose of vitamin B1 and folate separately but I do need these in higher amounts as I have deficiency in both these, and always have good levels of b12 so no need to supplement that but the rest low dose in the B minus is fine,

Some b vitamins can affect blood tests not sure if its just biotin or others so for a week before blood tests I stop mine. Again check on here and some one will give a better idea of which ones and for how long.

how are you treating adrenals?

Thyroid_mum profile image
Thyroid_mum in reply to

CytoQuel; Energy Multiplex and HPA Control along with DHEA - recommended by my Endo

in reply toThyroid_mum

I really don’t think these will be anywhere near enough. Adrenals need to be treated as precisely as thyroid, supplements are often not enough. ACE is the only supplement that would really be able to shift low cortisol otherwise it’s hydrocortisone x

Thyroid_mum profile image
Thyroid_mum in reply to

I don’t have low cortisol though, I have high cortisol and low DHEA

in reply toThyroid_mum

In that case you need something like PS100. Is it high across the whole day?

What does your iron look like? This can also create symptoms on T3.

Thyroid_mum profile image
Thyroid_mum in reply to

it shoots off the scale at 11 and is normal by bedtime

Thyroid_mum profile image
Thyroid_mum in reply to

need to do iron, ferritin is good.

in reply toThyroid_mum

a very high quality CBD oil would be good too, but it does need to be confirmed that you have high cortisol across the board and not just a mix of highs and lows

Not what you're looking for?

You may also like...

Unpleasant 'reaction' to T3?

Hi As a result of secondary hypothyroidism I have been taking T4 (150) for 2 years. Upon advice...
Trademole profile image

Should I increase T3?

Thanks to everyone who replied to my last post about starting T3. I did 4 days on just 2.5mcg...

Struggling introducing T3

Hi all, I knew I’d be back before too long as I’m totally useless when it comes to introducing...
TiredMummy profile image

When to increase T3 and reduce Levo??

So I started on T3 on Wednesday given to me by the NHS luckily! Iv started very slow because I'm...

T3 only, times and dosage experiences welcomed.

I have been on T3 only treatment since March this year and am currently dosing 2.5mcg at 09.00,...

Moderation team

See all
Jaydee1507 profile image
Jaydee1507Administrator
PurpleNails profile image
PurpleNailsAdministrator
SlowDragon profile image
SlowDragonAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.