Thyroid and brain fog

[ttendfriendpa]

years ago I posted about having onset of brain fog overnight. Tracked levels as group suggested and had synthroid adjusted to no avail.

for 7 years had brain fog and no specialist (4) could provide a reason for sudden onset or cause.

what cleared the brain fog was spironlactone 25mg taken every other day prescribed by my cardiologist.

i am female, 72 yo and live in US.

hope this information helps someone.

please do not respond to my comment.

[ttendfriendpa]

more information - chronic treatment with spironolactone causes a reduction in ischemic cerebral infarct size. Our hypothesis was that cerebral vascular structure is improved, via an increase in cerebral vessel lumen diameter, by chronic administration of spironolactone and that these changes would occur without a reduction in blood pressure. The MCA lumen and outer diameters were larger in the spironolactone-treated SHRSP compared to control SHRSP over the range of pressure.

There are two novel findings of this study:

1) Spironolactone treatment increases tone in the MCA of SHRSP and

2) Spironolactone treatment alters vascular structure of the MCA by increasing the lumen and outer diameters, without a change in blood pressure. When combined, these changes may explain the protective effects of spironolactone on the outcome of ischemic stroke, as observed previously by our laboratory

(Dorrance et al., 2000; Dorrance et al., 2001).

Spironolactone Improves Structure and Increases Tone in the Cerebral Vasculature of Male Spontaneously Hypertensive Stroke-Prone Rats

[ttendfriendpa in reply to ttendfriendpa]

BTW - my blood pressure was usually 110-120 over 65-70 from my 20’s to 60’s until I had a heart attack at the age of 66. So bp measurement is not necessarily indicative of blood pressure in the brain.