Experiences with 75mcg Levothyroxine (Teva)? - Thyroid UK

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Experiences with 75mcg Levothyroxine (Teva)?

Yasai profile image
13 Replies

I have some questions about specifically the Teva 75mcg Levothyroxine. Increased my dose recently from 50mcg, but recently started waking up with headaches, dizziness and blurred vision which never happened before on 50mcg.

Curious if this is just my body not liking the Teva brand, and maybe trying a generic one instead, or if I need to go back to 50mcg. Having a sight test to check my vision hasn't changed (my father has glaucoma and the vision change set off alarm bells for me working in optometry), but this is the only other thing I've changed recently.

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Yasai
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SlowDragon profile image
SlowDragonAdministrator

What were your blood test results that caused dose increase in levothyroxine to 75mcg

How long had you been left on just 50mcg levothyroxine

which brand of levothyroxine were you taking on 50mcg levothyroxine

Many people find Levothyroxine brands are not interchangeable.

Many patients do NOT get on well with Teva brand of Levothyroxine.

Teva contains mannitol as a filler, which seems to be possible cause of problems. Teva is the only brand that makes 75mcg tablet. So if avoiding Teva for 75mcg dose ask for 25mcg to add to 50mcg or just extra 50mcg tablets to cut in half

But for some people (usually if lactose intolerant, Teva is by far the best option)

Glenmark or Aristo (100mcg only) are lactose free and mannitol free. May be difficult to track down Glenmark, not been available very long 

Most easily available (and often most easily tolerated) are Mercury Pharma or Accord

Mercury Pharma make 25mcg, 50mcg and 100mcg tablets 

Accord only make 50mcg and 100mcg tablets 

Accord is also boxed as Almus via Boots, and Northstar 50mcg and 100mcg via Lloyds ....but Accord  doesn’t make 25mcg tablets

beware 25mcg Northstar is Teva

List of different brands available in U.K.

thyroiduk.org/if-you-are-hy...

Posts that mention Teva

healthunlocked.com/search/p...

Teva poll

healthunlocked.com/thyroidu...

Once you find a brand that suits you, best to make sure to only get that one at each prescription.

Watch out for brand change when dose is increased or at repeat prescription.

Government guidelines for GP if you find it difficult/impossible to change brands 

gov.uk/drug-safety-update/l...

If a patient reports persistent symptoms when switching between different levothyroxine tablet formulations, consider consistently prescribing a specific product known to be well tolerated by the patient. 

academic.oup.com/jcem/artic...

Physicians should: 1) alert patients that preparations may be switched at the pharmacy; 2) encourage patients to ask to remain on the same preparation at every pharmacy refill; and 3) make sure patients understand the need to have their TSH retested and the potential for dosing readjusted every time their LT4 preparation is switched (18).

Levothyroxine is an extremely fussy hormone and should always be taken on an empty stomach and then nothing apart from water for at least an hour after

Many people take Levothyroxine soon after waking, but it may be more convenient and perhaps more effective taken at bedtime

verywellhealth.com/best-tim...

markvanderpump.co.uk/blog/p...

No other medication or supplements at same as Levothyroxine, leave at least 2 hour gap.

Some like iron, calcium, magnesium, HRT, omeprazole or vitamin D should be four hours away

(Time gap doesn't apply to Vitamin D mouth spray)

If you normally take levothyroxine at bedtime/in night ...adjust timings as follows prior to blood test

Similarly if normally splitting your levothyroxine, take whole daily dose 24 hours before test 

Bloods should be retested 6-8; weeks after each dose change or brand change in levothyroxine

If testing Monday morning, delay Saturday evening dose levothyroxine until Sunday morning. Delay Sunday evening dose levothyroxine until after blood test on Monday morning. Take Monday evening dose levothyroxine as per normal

Essential to test vitamin D, folate, ferritin and B12 at least once a year

what vitamin supplements are you currently taking

REMEMBER.....very important....stop taking any supplements that contain biotin a week before ALL BLOOD TESTS as biotin can falsely affect test results - eg vitamin B complex

Yasai profile image
Yasai in reply to SlowDragon

The GP suggested trying a dose increase as my energy levels and fatigue have gotten worse. Blood test results indicated we have wiggle room to try an increased dose but it won't be the end of the world if it doesn't work.

I was taking Accord 50mcg before this, went into this cautiously because I know a lot of people don't get along with Teva. I'll talk to the GP about getting 25mcg MercuryPharma as I've had that before and haven't had any issues.

Had a sight test today, having had my last one 2 months ago, and my prescription has changed quite a lot. It's absolutely the Teva that's done this so I suppose it's back to the drawing board for the time being.

SlowDragon profile image
SlowDragonAdministrator in reply to Yasai

how much do you weigh in kilo

Guidelines are to increase dose levothyroxine slowly upwards in 25mcg steps until on approx 1.6mcg levothyroxine per kilo of your weight per day

some people need higher dose, some not quite so much

Levothyroxine doesn’t top up failing thyroid, it replaces it

When adequately treated on levothyroxine TSH will always be below 2. Many people will have TSH around or under one. Most important results are always Ft3 followed by Ft4

Ft3 at least 50% through range

What were your last test results and ranges

Yasai profile image
Yasai in reply to SlowDragon

My Serum TSH level was 3.8mlU/L. Didn't get T4 tested last time around for some reason although I did request it. I don't know exactly what my weight is but I'm aware I've lost weight recently due to my job.

SlowDragon profile image
SlowDragonAdministrator in reply to Yasai

once you get brand that suits you…..retest 6-8 weeks after any dose change or brand change in levothyroxine

Jaydee1507 profile image
Jaydee1507Administrator in reply to Yasai

Just go back to your GP, explain the issues you've had with the Teva brand and get a new prescription written and get a different brand. No need to quit yet when you have room for an increase.

Yasai profile image
Yasai in reply to Jaydee1507

This is the plan, other than this issue I've felt a lot more alert and less tired so I don't want to give up on increasing the dose slightly yet.

Buzcat profile image
Buzcat in reply to SlowDragon

you say Mercury Pharma is available could you tell me where as it’s not available in Glasgow areas.

SlowDragon profile image
SlowDragonAdministrator in reply to Buzcat

it’s available across U.K.

Pharmacies often have it listed by company name - Advanz

Mercury Pharma and Eltroxin are identical

Available as 25mcg, 50mcg and 100mcg tablets

Mercury Pharma customer care phone number 

healthunlocked.com/thyroidu...

BiscuitBaby profile image
BiscuitBaby

hi Yasai

I recently was given teva and I'd never had it. Within a few days I felt sick, funny tummy and generally feeling off. My heart rate had gone up too. I got the brand changed and those symptoms have gone. You could try increasing your dose using different tablets. Or speak to pharmacist. Mine is always very helpful.

helvella profile image
helvellaAdministratorThyroid UK

If you think there is something about this make, this dosage, or the specific packet in your hand, please put in a Yellow Card report.

Yasai profile image
Yasai in reply to helvella

I'm planning to, my prescription went up a few steps in a week when before this it hadn't changed in years. Had a headache all day because my current glasses don't match the prescription change.

Really hoping this will go back to normal once the Teva Levothyroxine is out of my system. 😔

crimple profile image
crimple in reply to Yasai

Yasai, I also had issues with TEVA. Easiest way to get correct dose is to get 50mcgm Accord tablets and split them with a pill cutter or craft knife. That way you can always have Accord. I did this for a number of months until I needed 100mcgm and then was prescribed 100mcgm tablet, got 50mcgm tablets again to split when I needed to go higher.

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