Dry mouth and insomnia on levothyroxine

[Experiment1982739903]

On 50 mcg, I experienced very dry mouth. When I went up to 100 mcg, I felt the dry mouth got much better but not completely resolved and also insomnia was much better. I've been on as high a dose as 300 mcg but that didnt fix the issues. Im down to 188 mcg and it feels about as bad as it was on 50 mcg...Im thinking to try a combo of t4 and t3. Maybe 125 mcg T4 and 30 T3. The dry mouth was much better near 100 mcg T4. Plus I heard someone on here who switched from T4 to T3 and the dry mouth resolved. Any thoughts or experiences would be much appreciated.

[Jaydee1507 Administrator]

You've posted thyroid results, but many hypo people suffer from low vitamin levels which can result in a host of unpleasant symptoms. Do you have any test results for ferritin, folate, B12 and D3?

[Experiment1982739903 in reply to Jaydee1507]

Thats true. My D3 is good now, B12 was like 443, range (200-1200). I started supplementing with methylcoblamin and methylfolate and it seems to help a lot with energy, but dry mouth and insomnia still there. Never tested folate...I have too much ferritin as I just recently learned I have heriditary hemachromatosis...Im experimenting with other supplements now. Coq10 doesnt seem to help. Ive tried 600 mg and dont feel anything yet. It was shown to increase saliva flow in a few experiments. No luck yet. Maybe try sea buckthorn next. Dont know. Thanks for responding

[HowNowWhatNow in reply to Experiment1982739903]

Have also had terrible dry mouth on T4 only.

Agree with your hypothesis on T3.

I had repeat salivary gland infections caused by dry mouth at the start of this year. I wondered if any of it was to do with sugar or glucose intake, too, as it happened after Xmas and eating a lot of food.

[Jaydee1507 Administrator in reply to Experiment1982739903]

Its worth actually testing for non optimal levels, otherwise you will forever be stabbing around in the dark.

[SueHG]

I had a very dry mouth for years before Dr P suggested I should stop t4 and start t3. Along with many other symptoms that go along with Hypothyroidism I was very ill. However almost as soon as started the new regime I began to feel better and have been now for some years. I do have to go to Greece to buy T3 as I have never ever been able to see a endo and my GP doesn’t want to know . I have managed at last to get a T3 blood test from my surgery now which is a minor miracle. I would never ever go back onto T4 as it was killing me. Because I was ‘starved’ of T3 because of non conversion I had a total heart block because of heart damage and now have a pacemaker. Why doctors and endos don’t realise the danger of non conversion I have no idea, it would help 1000s of people if doctors were better informed. Good luck

[Experiment1982739903 in reply to SueHG]

Thanks for sharing. Thats very helpful to me...Sorry you went through this