Sertraline

[Alice70]

Hi has anyone found that sertraline has interfered with there levothyroxine

[Lalatoot]

Alice. It is well documented that taking an ssri of which setraline is one, can interfere with orally taken thyroid hormones and that some folks might need a slightly higher dose of levo as a result.

This is because the anti d alters the levels of serotonin. Much of your serotonin is in your gut so gut function alters. This in turn can affect your absorption of levo hence the need for a higher dose.

Dont take your levo and setraline together.

[Alice70 in reply to Lalatoot]

Thank you so much for answer,i have taken levothyroxine for many years ,been on antidepressants for two half month ,last week i went to feel awful ,kept saying im getting the syptoms of of low thyriod ,now i know that sertraline can interfere with levo ,ill get my gp to test blood

[Buddy195 Administrator]

I hope the Sertraline works for you Alice 70. I know that some people who take either an SSRI (or HRT)need their thyroid medication adjusting upwards slightly . It’s best to test your thyroid levels first before making any changes, Do share any results with us so we can better advise.

[Alice70 in reply to Buddy195]

Will do Buddy ,speaking to my gp tomorrow about blood test

[Sofie007]

Hey Alice, for me it really made me more hypo. As Lalatoot wrote the sertraline interferes with the levothyroxine. I was very tired when I was combining them. I hope you find what works for you, i think upping the levo dose will do the trick.

[Alice70 in reply to Sofie007]

I think it is making me more hypo too ,did you come of sertraline or did your gp up your levothyroxine

[Sofie007]

I came off sertraline slowly because I want to focus on getting my thyroid levels better. A slow thyroid can be the cause of mental problems so it might solve them. If my thyroid is better and I still feel anxious I will try sertraline again.

[Alice70 in reply to Sofie007]

Thank you for your answer Sofie hope things work out well for you

[adin]

Hi, Why not try another ssri that interferes less with the thyroid eg Lexapro. Anyway, if you take levothyroxine in the morning, ssri is taken in the evening around 6- 7 pm.

[Alice70 in reply to adin]

Thanks adin ,not sure if my thriod has gon down with sertraline, feels like it has ,im going to try speeking with gp in the morning for blood test