Hello. It might not help but endo suggested that t3 (alone or even with t4) might cause heart problems, hair loss etc etc , and atrophy the thryroid so it cannot come back to life .
Has diogenes or anyone else research papers that i can use to try (!!) to convince them otherwise?
thanks
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lauriegraham
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hmm .. well not sure mine is dead .. just not converting .. think pituitary/cortisol system not stimulating thyroid so still hope for it to get going .. using t3 to try to get something moving but not to much effect so far .. so the question is, can it start up again after medium term t3 use?
ask endo to explain his thinking .. if using T4 doesn't atrophy 'otherwise healthy' thyroid tissue... why would using T3 ? (by what mechanism does he think this atrophy is caused) as far as i've read thus far in research papers when asking myself this question ,... if you don't use a thyroid it just sits there being bored, it doesn't shrivel up / shrink / atrophy ..... T(SH)Rab (of the 'blocking' sort, not the stimulating sort ) may be responsible for thyroid atrophy , but i doubt T4 or T3 can do it.
in fact the idea that T3 would atrophy a thyroid gland is a bit illogical.. the thyroid makes T3.... why would it make something that shrunk itself ?
put on your best ' fascinated student ' face and ask him to share the references/ sources he's seen this suggestion in .
This is a link to Dr John Lowe's publication. He is now deceased due to an accident but took T3 himself and did his research of T3 as a teenager and became a doctor and expert in T3.
He would only prescribe NDTs (natural dessicated thyroid hormones - removed by the 'supposed to be experts' in the British Thyroid Association despite it restoring many people's health since 1892. He gave his patients Natural Dessicated Thyroid Hormones but if any were 'resistant' he prescribed T3 alone (liothyronine).
Too much levothyroxine, liothyronine or NDT can cause the thyroid atropy in time but as far as I know it can recover. This is not the same as thyroid damage caused by autoimmune attack which is not reversible. My TSH was completely suppressed by very high dose levothyroxine / liothyroine for a decade and recovered after a trial of coming off hormone.
The evidence I've seen shows that levothyroxine (strictly speaking thyroxine - T4) is more harmful than liothyronine (T3), especially for cardiac damage and cancer. See my post healthunlocked.com/thyroidu... .
This is rather unexpected, I expected liothyronine woudl carry more risk than levothyroxine, primarily because taking T3 bypasses the D1 and D2 deiodinase mechanisms which probably have a protective mechanism. However, it turns out that T4 has non-genomic actions that do cardiovascular harm and promote cancer. (non-genomic means effects that don't work via thyroid hormone receptors - the main way thyroid hormone works).
I am sorry to state that he is wrong. T4 (levo) caused me to have severe palpitations and even cardiologist couldn't figure out why this was happening (always middle of night).
When T3 was added to T4 I felt an immense improvement but T3 alone resolved any symptoms. Previous to taking T3 sometimes I had a pulse (middle of night) above 144 bpm.
One of Thyroiduk's scientist/researcher/doctor/expert on T3 (deceased due to an accident) took his dose of T3 in the middle of the night so that nothing interfered with its uptake.
Well, if that's the Endo's opinion it is wrong. Dr John Lowe, now deceased due to an accident, was an Adviser to Thyroiduk before his accidental death.
Dr Lowe, himself, took T3 alone to relieve him of clinical symptoms of hypo.
I shall give you a link and hope it is helpful.
I take T3 when I awake and swallow with one glass of water and wait an hour before I eat. I have no clinical symptoms and feel well and energetic.
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