Understanding test results

[Rowing2]

Can anyone explain what these results mean? I’m just compiling a letter to my gp as I feel I never have time and forget things when on the phone and I didn’t understand a few bits from my last test.

Tissue transglutaminase 1gA level(XaJg2) 0.6 u/mL (0.0 - 10) test outside Skopje of UKAS accreditation. For new NICE guidelines on diagnosis of coeliac disease please see nice.org.U.K./guidance/ng20

Serum C reactive protein level <4mg/L (0.0-10.0)

Thank you.

[nellie237]

Hi Rowing2,

The Tissue transglutaminase 1gA level looks negative , although a negative TTG does not rule out the possibility of being Coeliac. If you were tested for Coeliac due to Coeliac symptoms, you should be referred to Gastro, and you will need to keep eating gluten until told otherwise. If you were tested because of a new thyroid diagnosis I don't think that they will investigate further.

I was tested for Coeliac when dx Hashi's in 2007 which came back negative. Roll on 13yrs, and I tested positive, so.....personally I think the advice given on here for AIT people to adopt a gf diet after ruling out Coeliac is very sound advice. It would have saved me a whole heap of pain, and even more debilitating was the lethargy due to very low nutrients. Coeliac put me in bed every afternoon (which is when I found this forum).......Hashi's didn't, and I was very, very undermedicated for the 1st few years.

Getting a positive diagnosis has only 1 benefit..........it is recommended to test the following annually

full blood count,

ferritin,

serum folate,

vitamin B12,

calcium,

alkaline phosphatase

associated autoimmune conditions (thyroid-stimulating hormone and thyroid hormone(s),

and serum glucose),146 147

liver disease (aspartate aminotransferase/alanine aminotransferase)40 and

dietary adherence (anti-TG2 or EMA/DGP)

where there aren't any guidelines recommending these tests for Hypo's.

I was curious about "test outside Skopje of UKAS accreditation" and found this explanation from the Royal Marsden

"Where this is the case, services users can have confidence in the results of these tests as the

Laboratories will operate them under the same stringent conditions of quality and

competence as for accredited tests and will usually be working to achieve accreditation of the tests"

shared-d7-royalmarsden-publ...

My understanding is that CRP is a non specific marker for inflammation, and would need to come back significantly over range for a GP to investigate

[Rowing2 in reply to nellie237]

Thank you so much for your advice, I’m really grateful