Immunglobulin: Sorry, another post for today! In... - Thyroid UK

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Immunglobulin

Annieza profile image
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Sorry, another post for today!

In my recent blood tests, my IgE results were through the roof and the doc says it was high in 2018 too, round about when my hair loss started and I tested for antibodies which were high.

Does anyone know if this is linked to Thyroid issues or raised antibodies?

My report states:

Immunglobulin IgE 735 (range 2-214)

Can be elevated in allergy, allergic bronchopulmonary aspergillosis, parasitic infections, and some inflammatory diseases and heamatological disorders.

It was around 800 in 2018 but my GP says its do with allergic reactions but we don't know what it could be and it can't be tested on the NHS.

Thanks!

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Annieza
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helvella profile image
helvellaAdministratorThyroid UK

Am anything but well-versed, but the Wiki article appears not too bad:

en.wikipedia.org/wiki/Immun...

My simplistic understanding is that the term antibody describes a function while the term immunoglobulin is used for the actual molecules that are antibodies.

radd profile image
radd

Annieza,

IgE is one of a group known as immunoglobins, our first line of defence of antibodies. IgE is usually associated with a severe allergy as the reaction is immediate. Not intolerance (as in delayed or built up reaction) but immediate actual runny noise, itchy rash, tongue swelling, breathlessness, vomiting, etc and can be due to anaphylaxis, or the release of large amounts of inflammatory chemicals such as histamine.

They are antibodies made to protect us, whereas our thyroid antibodies, known as auto-antibodies are made for self-attack. It is well known that one autoimmune condition invites another but I think once the immune system gets really messed up with elevated antibodies, it is also more susceptible to experience these other immune issues.

Have you got leaky gut or irritable bowel syndrome as these are thought to be the beginnings?

Annieza profile image
Annieza in reply to radd

thanks for your reply

I struggle with constipation and think I may have leaky gut as all my nutritional elements are within range but still have hair loss and constipation.

I have booked with a nutritionist to dig a bit deeper

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