What are peoples views on soy consumption with Hashimoto’s?

[ML44]

I’ve read contrasting things... to eat soy based products? Or not?

[helvella Administrator Thyroid UK]

This is based on rats - not humans. And "formula" not soy in all its many other forms. But it does add to the questioning over consumption of soy-based foods.

Minerva Pediatr (Torino)

. 2021 Apr 16.

doi: 10.23736/S2724-5276.21.06221-6. Online ahead of print.

Effects of soy-containing infant formulas on thyroid gland in rats

Serdar Çulcu 1 , Ebrar Akkaya 2 , Erhan Aysan 3 , Mirkhalig Javadov 3 , Alev Cumbul 4

Affiliations

Affiliations

• 1 Faculty of Medicine, A.Y. Ankara Onkology Hospital, University of Health Science, Ankara, Turkey - [e-mail].

• 2 Faculty of Medicine Student, Bezmialem Vakif University, Istanbul, Turkey.

• 3 Department of General Surgery, Faculty of Medicine, Yeditepe University, Istanbul, Turkey.

• 4 Department of Histology and Embriology, Faculty of Medicine, Yeditepe University, Istanbul Turkey.

• PMID: 33861048

• DOI: 10.23736/S2724-5276.21.06221-6

Abstract

Background: Effects of soy-containing infant formulas on the thyroid gland is not clear. We aimed to evaluate the effects of infant formulas with different quantities of soy content on the functional and histopathological characteristics of the thyroid gland.

Methods: Twenty-eight female Sprague-Dawley rats were divided into four groups. Group 1 was fed with standard pellet rat food (8g/day); Group 2 soy-free infant formula (8g/day); Group 3 low-dose (1.12g/100ml) soy-containing formula (8g/day), and Group 4 high-dose (2.64g/100ml) soy-containing formula (8g/day). Blood samples were collected from the subjects on day 0, 30, 60, and 90 to evaluate thyroid functions. All subjects were sacrificed on day 90. Thyroid glands were excised and examined histopathologically.

Results: Serum levels of free T3, free T4, TSH, anti TPO, and anti TG were significantly higher in Group 4 compared to other groups (p<0.001, p<0.01,p<0.001,p=0.002). No differences were found in the histopathological findings between the groups.

Conclusions: Infant formulas with high soy content induce hyperthyroidism with high TSH levels. High levels of anti TPO and anti TG suggest that observed changes might have occurred via inflammatory mechanism.

pubmed.ncbi.nlm.nih.gov/338...

[greygoose]

It's not just the effect soy has on the thyroid itself - that shouldn't bother you when on thyroid hormone replacement. But soy also impedes the uptake of thyroid hormones by the cells, meaning that you can have good levels in the blood, but because it's not getting into the cells, you still have the hypo symptoms.

Also, from what I've read, soy is not good for anyone to eat, not just hypos. It can cause all sorts of problems.

[fuchsia-pink]

Not