Do thyroid antibodies disappear once thyroid completely damaged

[Runnergirl]

Hi everyone

Just wondered, if thyroid antibodies fall down to normal range once the thyroid has been completely ‘destroyed’ and stopped working, my thyroglobulin antibody is slightly over range at 156 but that is the lowest level for 10plus years and it seems to be reducing each year.

Many thanks for your thoughts on this.

Runner Girl

[greygoose]

Yes, they do tend to. But, they fluctuate all the time, so could go high again. They're most un predictable!

[Runnergirl in reply to greygoose]

Thank you Grey GooseI was hoping this would be the final curtain! Obviously more complicated than I thought for some.

RG

[greygoose in reply to Runnergirl]

It can be very complicated, yes.

[jrbarnes]

This is a good question. Having been diagnosed 13 years ago my antibodies were never tested until last year which showed no TPO antibodies but thyroglobulin antibodies were flagged as high with no ranges given, which is not helpful, however the number given was '4.' That doesn't look very high. Leads me to believe the rest of my thyroid has been destroyed. I'm sensitive to the smallest change in thyroid hormone. Are you as well?

[Runnergirl in reply to jrbarnes]

Thanks for replying I had both antibodies in 2012 with the TPO back in normal range after 3 months, over the past 10 years the Thyroglobulin abs peaked at 500 but have steadily reduced every year since then.

I am hoping mine has been destroyed now, yes I do seem to be sensitive to changes like you, and add menopause to the mix it’s confusing!

[Lora7again]

I try not to worry about my thyroglobulin antibodies which are very high at 4000. They don't actually affect how I feel and I have tried to lower them without any success. At first the results did alarm me but after 4 years I have to just accept that they will always be high. Just to add my thyroid does still work and I have a multiodular goiter and I definitely don't have Hashi's.

[tattybogle]

In 2003 when diagnosed hypo my TPOabs were 2499 [0-50] and >3000 6 weeks later. 13 years later in 2016 they were 195....I don't know what they are now, and i've never had an ultrasound , so no idea how much if any thyroid gland i have left.

So this doesn't add much knowledge i'm afraid , just a comparison.

And then there's the menopause .... i still have problems with fT4/TSH going up/down for no apparent reason , so i'm starting to suspect that the sunny uplands of achieving stable thyroid levels once thyroid is completely caput are a place we might not get to , but i live in hope.

[Runnergirl in reply to tattybogle]

Thank you It’s good to compare what’s going on with other people, that’s exactly what I was hoping for but heyho!