Help with thyroid test results

[D9d9]

Most recent blood test results. I could do with some advice please. I have had a goitre sometime in the past.

[SeasideSusie Remembering]

D9d9

Related post: healthunlocked.com/thyroidu...

Have you found out yet what antibodies were tested?

Are you still on Carbimazole?

What were the results of thyroid tests that prompted the prescribing of Carbimazole?

[D9d9 in reply to SeasideSusie]

Ive sorted the picture thanks.

[SeasideSusie Remembering in reply to D9d9]

Go to the post with the picture in and click on MORE then from the pop up list click on EDIT then you can scroll down and click on REMOVE PICTURE.

There's nothing in your picture to identify you so there's no panic about that.

[D9d9 in reply to SeasideSusie]

Can you still see my posts? Im not sure if they are getting through?

[SeasideSusie Remembering in reply to D9d9]

Yes, your posts are visible.

[D9d9 in reply to SeasideSusie]

Yes, I believe its Se thyroid peroxidase Ab conc? Does that make sense?

[SeasideSusie Remembering in reply to D9d9]

D9d9

What was the antibody test result?

What were the results of the other thyroid tests that prompted the prescribing of Carbimazole?

[D9d9 in reply to SeasideSusie]

Antibody test thyroid peroxidase result was 0.2 U/ml. <9.0

[SeasideSusie Remembering in reply to D9d9]

Yes, you already mentioned that a few hours ago, 2 posts below in this thread and I responded to that post.

[D9d9 in reply to SeasideSusie]

Yes Id forgotten. Thanks, silly me.

[D9d9 in reply to SeasideSusie]

Ive just put up some older blood results

[SeasideSusie Remembering in reply to D9d9]

If you mean these:

Nov 20 2019 results were TSH 0.28 (0.35-5.50). T4 13.2pmol/L (7.0-17.0). 16 Nov 2019 TSH 0.21 T4 14.4 pmol/L

then I've already responded below that post, further down.

[D9d9 in reply to SeasideSusie]

Yes, Ive found them now. Thanks.

[D9d9 in reply to SeasideSusie]

These were the results that prompted Carbimazole. Waiting to have second blood test done as it is seven weeks now since starting drug.

[D9d9 in reply to D9d9]

Antibody test result was 0.2U/ml. <9.0 thyroid perixidase

[SeasideSusie Remembering in reply to D9d9]

D9d9

So, if I understand correctly:

TSH: <0.02 (3.5-5.5)

FT4: 21.1 (7-17)

TPO antibodies: 0.2 (<9.0)

and these prompted the prescribing of Carbimazole.

Was this your GP?

Assuming it was your GP who prescribed the Carbimazole, I think he jumped the gun.

To know if you definitely have Graves Disease (over active thyroid) you need TSI and TRAb antibodies tested and these have to come back positive to confirm this and then Carbimazole would be the correct medication.

TPO antibodies are negative but Tg (Thyroglobulin) antibodies haven't been tested and you can have Hashimoto's with negative TPO but positive Tg antibodies.

Hashimoto's can start with a transient "hyper" phase which is why it's essential to get all the antibodies tested before prescribing Carbimazole. All this was covered in replies to your original post here: healthunlocked.com/thyroidu...

I would have thought your FT4 wasn't high enough for true hyperthyroidism and could very well have been a false hyper that you get with Hashi's.

If this is down to your GP then you really should have been referred to an endo for further testing. GPs don't know enough (and not all endos do) and many GPs misdiagnose this.

[D9d9 in reply to SeasideSusie]

Yes it was a GP but I believe she spoke to endo re this and lowered carbimazole to 5 mg from few days of 40 mg. I think this was because if past Goitre that the hospital is aware of? As I am shielding my appointment with endo last yr was cancelled. Previous blood tests showed low TSH but T4 was Ok.

[D9d9 in reply to D9d9]

This was the first test where T4 was considered too high.

[D9d9 in reply to D9d9]

Is goitre a result of too much TSH or too little?

[SeasideSusie Remembering in reply to D9d9]

D9d9

Previous blood tests showed low TSH but T4 was Ok.

With or without thyroid meds/Carbimazole?

Can you post any previous results with reference ranges, say if you were taking any thyroid meds at the time.

[D9d9 in reply to SeasideSusie]

No medication for thyroid until now except a multivitamin.

[D9d9 in reply to SeasideSusie]

Nov 20 2019 results were TSH 0.28 (0.35-5.50). T4 13.2pmol/L (7.0-17.0). 16 Nov 2019 TSH 0.21 T4 14.4 pmol/L

[SeasideSusie Remembering in reply to D9d9]

D9d9

So those results just show a slightly below range TSH and a very normal FT4, and it is this more recent result:

TSH: <0.02 (3.5-5.5)

FT4: 21.1 (7-17)

TPO antibodies: 0.2 (<9.0)

that has prompted the prescribing of Carbimazole?

I don't think there is enough evidence to definitely say you have hyperthyroidism because I believe your FT4 would be a lot higher. But I am not medically trained. However, on seeing so many instances of wrong diagnosis on the forum, where members have been diagnosed hyperthyroid and given Carbimazole, without testing of the correct antibodies to confirm this, then I, like many others here, are sceptical when it comes to cases like yours. You could very well have Hashimoto's, you have only had TPO antibodies tested, you could do with having Tg antibodies tested also, although it's possible to have Hashi's without raised antibodies, and in that case an ultrasound of the thyroid would be helpful.

In your position I would be insisting on TSI and TRAb antibody tests to confirm Graves disease and the need for Carbimazole, as well as repeating TPO antibodies, testing Tg antibodies and an ultrasound.

[D9d9 in reply to SeasideSusie]

Thank you. I cant tell you how much it means to be able to get this help.

[D9d9 in reply to SeasideSusie]

Would taking Carbimazole effect results of any antibody tests taken now?

[SeasideSusie Remembering in reply to D9d9]

I can't answer that with absolute certainty. I've never taken Carbimazole and my antibody tests have always come back very low anyway. Carbimazole's role is to stop the thyroid gland from producing too much thyroid hormone which would show in test results by increasing TSH and lowering FT4. I don't believe it actually affects the thyroid antibodies at all but a better person than me ought to confirm that.

[tattybogle]

hi , are these the results after taking carbimazole for a few weeks ?

And did you manage to find out whether you'd been tested for graves antibodies (TRab) ?

or just the TPOab (thyroid peroxidase antibodies) / TGab (thyroglobulin antibodies) which confirm autoimmune hypothyroidism , but can also be present in graves hyperthyroidism.

GP's usually order the blood test for TPOab/TGab , where as it is usually only Endocrinologists that can order the TRab test to confirm Graves disease as the cause of hyperthyroidism

[D9d9 in reply to tattybogle]

Not on any thyroid medication when I had this blood test done and only thyroid peroxidase tested

[D9d9 in reply to tattybogle]

Can you still see my posts?

[tattybogle in reply to D9d9]

can see your previous one yes , if you click on your little picture next to your name it will take you to them.