This is not strictly relevant here, but its effects have significant implications in the difficulty of getting the present accepted TSH-driven thyroid function/disease paradigm to change.
I came across this quotation in a book by Stuart Ritchie: Science Fictions, which tell all about why science and especially medicine is so diminished in value and credibility. I quote:
"Anyone who reads journals widely and critically is forced to realise there are scarcely any bars to eventual publication. There seems to be 1) no study too fragmented, 2) no hypothesis too trivial, 3) no literature citation too biased or too egotistical, 4) no design too warped, 5) no methodology too bungled, 6) no presentation of results too inaccurate 7) too obscure or 8) too contradictory, 9) no analysis too self-serving, 10) no argument too circular, 11) no conclusions too trifling. 12) or too unjustified, 13) and no grammar and syntax too offensive for a paper to end up in print."
This is what honest scientific reporting is up against - a result of the action of grant giving to scientists based on the number of publications they make. It encourages all of the wrongful behaviour above. This includes thyroidology: I have seen several papers where the conclusions were completely at odds with what the data actually showed. It is a scandal which hinders advances in knowledge and inhibits the necessary changes in actions resulting from them.