Help with latest results please!!

[Joeblo77]

Hi guys can you give me advice this is my latest bloods! I feel terrible! On 100mg synthyroid about to go to 150mg

[SlowDragon Administrator]

Only increase by 25mcg at any one time

Retest in 6–8 weeks

Essential to test vitamins too

Vitamin D,folate, ferritin and B12

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .

Last dose of Levothyroxine 24 hours prior to blood test. (taking delayed dose immediately after blood draw).

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

[Joeblo77 in reply to SlowDragon]

Vit d perfect , folate 36 (>8)

[Joeblo77]

Iron is low but B12 is great!

B12 - 517 (130-650)

Iron - 9 (10-30)

Transferrin 2.4 (2.0-3.5)

Saturation 17% (20-50)

Ferritin 52 (20-200)

[SeasideSusie Remembering in reply to Joeblo77]

Joeblo77

Iron is low but B12 is great!

B12 - 517 (130-650)

Your B12 isn't necessarily great. What is the unit of measurment - pg/ml (or ng/L, they are both the same) or pmol/L?

If it's pg/ml or ng/L then according to an extract from the book, "Could it be B12?" by Sally M. Pacholok:

"We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebrospinal fluid below 550".

"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml."

If it's pmol/L then it's the equivalent of 700.5 so would be OK but might be better higher.

Iron - 9 (10-30)

Transferrin 2.4 (2.0-3.5)

Saturation 17% (20-50)

Ferritin 52 (20-200)

Optimal results for an iron panel, according to rt3-adrenals.org/Iron_test_... are:

Serum iron: 55 to 70% of the range, higher end for men - yours is below range

Saturation: optimal is 35 to 45%, higher end for men - yours is low at 17%

Transferrin: Low in range indicates lack of capacity for additional iron, High in range indicates body's need for supplemental iron - yours is 26.67% through range so would be classed as quite low

Ferritin: Low level virtually always indicates need for iron supplementation - yours is 17.78% through range

There is obviously a problem with your iron so you need to discuss this with your GP as this could very well be causing problems. You may be looking at iron deficiency going by your serum iron level. Have you had a full blood count to see if you have anaemia?

What is your "perfect" Vit D level?

Do you have Hashi's?

[fuchsia-pink]

It's good that you're getting a dose increase as free T4 and free T3 are both extremely low - free T4 only 9% through range and free T3 even worse - scraping along right at the bottom at less than 3%. You must feel absolutely dreadful!

Please don't let your GP obsess about your TSH -currently in range but quite low - it's the actual thyroid hormones that matter - and you will probably want these to be in the top third - maybe the top quartile - of their respective ranges to feel tip-top.

I expect it'll take a few 25 mcg increases to get there ... so be patient x

[Joeblo77 in reply to fuchsia-pink]

Thanks hun yes I’m wiped out my iron is shocking too not sure why nothing much has changed!! The tiredness and headaches constantly are enough to push one over the edge! Not to mention the creeping weight!! I hope the increase will help me and that he doesn’t stop it if my Tsh goes lower he doesn’t understand thyroid at all I had to point out that my t4 and t3 were not very high 🤦‍♀️ Any tips on how I can improve my conversion or will this naturally improve with a better t4 dose?

[fuchsia-pink in reply to Joeblo77]

Your levels are so awful it's difficult to see how well you convert ... so I'd prioritise dose increases in levo until your free T4 is where it should be - and then see how your free T3 is managing. Both should improve with a dose increase, albeit not necessarily at the same level. Good luck x