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revkrow profile image
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Is Hashimotos Thyroiditis an underlying auto-immune condition that will raise concerns in ability to fight off Covid 19?

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revkrow
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Angel20 profile image
Angel20

There is a learning curve with coronavirus it attacks the lungs. As a precaution those with Graves Disease and Hashimotos should take extra care to protect themselves

RedApple profile image
RedAppleAdministrator in reply to Angel20

Angel20, where did you get this info from please? Personally, I would say that everyone should take extra care to protect themselves. :)

Treepie profile image
Treepie in reply to RedApple

The Irish Government have put folk with poor immune systems on their at risk list.

I did like the the proposal from yesterday to go about your business as if you are infected .

RedApple profile image
RedAppleAdministrator in reply to Treepie

The question is whether autoimmune thyroid disease equates to a poor immune system. So far, this has never been clarified. There has been suggestion that autoimmune thyroid disease is more about an over zealous immune system.

Treepie profile image
Treepie in reply to RedApple

Yes ,in that it is attacking our own cells, but that weakens us and maybe makes us vulnerable to other attacks. My antibodies were very high when first tested but have been below threshold for three years . Chemo has also had an effect this last year so I guess my immune system is now weak.

Cooper27 profile image
Cooper27 in reply to RedApple

I asked this question to a gastroenterologist who was answering questions on coeliac disease (but because autoimmune diseases can be linked, I asked about Hashimotos too). Basically, any autoimmune disease will weaken you immune system to about 95%. It leaves you at an increased risk of catching something but it doesn't really influence how fit you are to fight it off.

distractonaught profile image
distractonaught in reply to RedApple

I'd love to get some clarity on this. At my last test, my antibodies were off the scale - I definitely 'go down' with seasonal viruses more often than most people do (I tend to get ill about half a dozen times a year and my boyfriend gets ill maybe once or twice at most) but never related it to my thyroid before now.

McPammy profile image
McPammy in reply to RedApple

That is what happens eventually if you are really bad with pneumonia which can happen to a small percentage with Covid-19. Eventually ones antibodies goes into overdrive and next thing it’s organ failure. Essentially people with Hashimotos have suffered thyroid failure due antibodies going into overdrive attacking it and destroying it eventually.

Smotv80 profile image
Smotv80 in reply to RedApple

This is exactly my logic. I have been desperately trying to find out whether Hashi's have a weakened immune system, but there is nothing definitive anywhere. So my own conclusion is that my immune system seems to always be on high alert looking for a fight! If anything they will be all over a virus!

ShootingStars profile image
ShootingStars in reply to RedApple

See at the bottom about the comorbidity for Hashimoto's and Graves with Immunoglobulin Deficiency. Immunoglobulin Deficiency causes frequent infections.

Angel20 profile image
Angel20 in reply to RedApple

of course everyone should take care, all I was saying with auto immune diseases we should take care because coronavirus is new it is a learning curve even for the Scientists

revkrow profile image
revkrow in reply to Angel20

Thank you

RedApple profile image
RedAppleAdministrator

revkrow, The info on the BritishThyroidFoundation website suggests not. btf-thyroid.org/news/thyroi...

revkrow profile image
revkrow in reply to RedApple

Thank you

ShootingStars profile image
ShootingStars in reply to RedApple

Yes, if you get frequent infections and have an immunoglobulin deficiency. My response at the bottom has detailed information.

You would be wise to ignore advice to the contrary, especially from "official" thyroid sites such as BTF or BTA, sites which endorse the ban on liothyronine and NDT.

Take all the care you can as an immune system which is not working effectively leaves you open to all sorts of nasties; in my case it was cancer.

Now on NDT and, at 72, feel I can easily defend myself against this virus.

Perhaps in years to come we may learn the truth about Hashi and coronavirus. In the meanwhile don't throw caution to the wind.

Hashimotos in an overactive immune system, not a weak immune system. One thing is having high thyroid antibodies and another having low white cell count. Everyone is different, but like everybody right now, protect yourself, stay home if you can, wash your hands, practice social distancing. Stress lowers our immunity greatly, so try to relax and do something nice for yourself.

ShootingStars profile image
ShootingStars in reply to

Or, having an Immunoglobulin Deficiency, which causes frequent infections. My post below has details and associated links. If you do not have enough IgM or IgG, you cannot fight off infections.

Harle profile image
Harle

I have Hashimotos and even though my immune system seems to be in overdrive I will come down with every single thing that’s going around! So if my gut biome and my cortisol are not optimal My immune system is compromised!

I read an article yesterday that says Hashimotos is a chronic illness and as such places sufferers into the high risk group! This was from thyroid advocate Mary Shomons advice page!

Perhaps you could look there for further advice!

ShootingStars profile image
ShootingStars in reply to Harle

You might have an immunoglobulin deficiency. If you don't have enough immunoglobulins, you cannot fight off infections and get sick frequently. Hashimoto's is comorbid for Common Variable Immune Deficiency (CVID) and Selective IgM Deficiency (SIgMD). My post below has details about it and links.

Tula2017 profile image
Tula2017

I have Hashimotos and ever since my neutrophils count has been below the range and my temperature around 35,

When I catch something I take longer than anyone in the family to recover and also if it goes to my chest I need antibiotics to shake it off.

I consider myself at increased risk.

HLAB35 profile image
HLAB35

Inflammation is the issue, I believe, in all of us with autoimmune issues. Lungs are more prone to inflammation if vitamin D levels are poor.... there have been several studies on how respiratory illness is worse in those with low vitamin D. Also, lungs need to clean up with half an hour's worth of fresh air a day.

So, my feeling is that social distancing - when you and your household have no symptoms - should be done and DO get some fresh air and sunshine by going for a walk, gardening etc..

If you know you have low vitamin D - follow the admin team's knowledgeable advice. Also, take Magnesium it's a co-factor (soluble is good, so is transdermal) at the very least, because a) it massively assists vitamin D absorption and b) it relieves anxiety / depression and stress and inflammation. Look into other cofactors as well.

Also, bear in mind Dr Sarah Myhill's advice on improving stomach acid levels as stomach acid kills pathogens. Vitamin C kills pathogens too.

Alanna01 profile image
Alanna01

Well I can only talk for myself. I have asthma and hashis.

It used to be that I would live in fear of catching a cold because it would go straight to my chest. Always catching throat infections, tonsilitis etc every single year. I learned to keep a stash of antibiotics on hand.

Then for whatever reason (ironically after the worst cold in my life) the hashis ramped up massively.

I now very rarely catch colds or anything. No chest infections, no tonsilitis. I might get one cold a year or none. I am more allergic however and also now have fibromyalgia. I think rather than a weak immune system I have an overactive one.

That's not to say I'm not vulnerable as I still have Asthma and this virus seems unpredicatable. But in terms of the hashis I dont feel it contributes to my vulnerability.

Of course hashi patients are often low in vitamins so there may be vulnerability in that sense.

Gelliott profile image
Gelliott in reply to Alanna01

Your history sounds very similar to mine and I notice more allergies now, ceoliac being a big one and a cold sore virus which flares up constantly. This isn't on my lip but, of all places, on my left buttock. Doctors are confused and tried everything from Zovirax, treating it topically, to Aciclovir for shingles.

Like you, I don't appear to pick up colds and flu easily and always have my annual flu jab.

I take a probiotic and turmeric capsule daily, but as you say maybe need to look at a multivitamin. I also have to take VitD with calcium prescribed, for osteoporosis. This concerns me as some people have said the calcium is not a good thing to take. Would love an opportunity to discuss with my doctor but they cannot spare the time.

Should have a Bone Density Scan this month, but very likely to be delayed due to the worldwide situation.

Stay safe and wish you good health.

McPammy profile image
McPammy

I’d rather be safe than sorry. So I’m definitely protecting myself as much as I possibly can. Our thyroids if Hashimotos have been destroyed by antibodies going into overdrive attacking the thyroid. Why this happens I’m still trying to understand. Best to eat as much good food to boost your immune system. Stay fit as possible and drink water. And keep a good distance between yourself and others if you go out. I’m staying in more. Decided to decorate my entire house while all this is going on.

I do believe I’ve recently had the virus as I had the symptoms but found it impossible to get through to 111 before the directive changed not to call them. I just wanted a test but couldn’t get one. I don’t know for sure if I actually did have it now. But I’ve never had a dry cough, fever and breathing difficulties ever before in my life that I can remember.

SickLeo17 profile image
SickLeo17 in reply to McPammy

Hopefully one day they will have a serum test to check for antibodies for this virus. Just like they can do for Rubella and Glandular Fever.

Angel_of_the_North profile image
Angel_of_the_North in reply to SickLeo17

All an antibody test does is show that you have at some time been in contact with a virus or whatever (so if you had measles as a child, you'll have measles antibodies). So not really very useful in this case.

kalel profile image
kalel in reply to SickLeo17

Maybe I will be wrong but my main understanding a bit like with SARS this is a pandemic but unless there is scientic proof to say otherwise the virus will just die off. Even if people chose to take a vaccine, look at the SARS vaccine it is useless now. We will see what happens but most people are saying the summer months are hot enough the virus will die off, of course there is a lot of different info out there about what will happen as well but I know there is a massive campaing going on, online urging people to stay home as much as they can, because as I am sure a lot of us know, there are also people out there who have the virus and carry no symptoms. So it is unknown terrority and just gotta things day by day, I think.

RockyPath profile image
RockyPath

Yes, autoimmune conditions are a risk factor for dire outcomes from COVID-19. The immune response floods the lungs with debris, causing sometimes fatal pneumonia.

Received the following from pharmacy:

“A significant portion of our orders travel in the cargo areas on passenger planes. Without passengers to fly on those planes, the cargo that would otherwise travel on passenger planes might also not travel or become prohibitively costly to transport if there are further flight cancellations. To date, we have been able to successfully re-route the delivery of orders but there is a significant risk that air traffic will be curtailed further. Please be advised, however, that this re-routing is causing delays in delivery of an additional one to two weeks relative to our standard delivery times.

Second, global supply chains in numerous industries are affected. When it comes to pharmaceuticals, the vast majority of the active pharmaceutical ingredients or their components used to produce finished dosages in the entire worldwide prescription drug supply chain, including the drugs sold in the United States, are manufactured in China, where the coronavirus has had the most impact on factory production to date. Further complicating things is that some countries, including those our suppliers source products from, have begun to ban the export of at least certain pharmaceuticals in an effort to preserve supplies for their local populations. At this time, we have access to adequate supplies of most of the products we offer but we do not know whether this will remain the case.”

Miffie profile image
Miffie in reply to RockyPath

With respect most on this site are UK based I think. I think you are in the USA? It would help if you tell us which pharmacy this has come from.

The USA and the UK are dealing with the virus very differently which can also “muddy the waters”. Take care.

RockyPath profile image
RockyPath in reply to Miffie

The email with the declaration of ingredient shortages came from a pharmacy in British Columbia. An article in the European Data Journalism Network several days ago bemoans how Europe's pharmaceutical companies have come to depend on cheap Chinese supplies of the raw materials for their products.

europeandatajournalism.eu/e...

"The COVID-19 outbreak has revived fears over acute drug shortages in Europe, sparking calls to repatriate the production of pharmaceutical ingredients from China. But rebuilding capacity would take years, if it were even possible."

StitchFairy profile image
StitchFairy in reply to Miffie

Miffie I'm sure the availibility of medicines will not be so vastly different in the UK as it is in the US. The UK isn't anything like self sufficient when it comes to medication. We too have to import raw ingredients and medicines from various other countries. The bit about cargo and passenger planes is just as applicable to the UK.

Miffie profile image
Miffie in reply to StitchFairy

Why would you want to say that to me? I did not say it did not apply to the UK. Kind of you to take time to inform me of the situation when you are worried I am unaware of the facts. I always appreciate help from those with greater knowledge than I.

On this occasion you have reassured me that I was not wrong to think that the UK does not secret laboratories producing all the medication the population would need if an occasion such as the current pandemic occurred. In deed you have reinforced the tiny bit of awareness I have about manufacture of pharmaceutical drugs. However thank you again for your time and kind sharing.

ShootingStars profile image
ShootingStars in reply to RockyPath

Yes, especially if you have an Immunoglobulin Deficiency. Hashimoto's and Graves are comorbid for Selective IgM Deficiency and Common Variable Immunoglobulin Deficiency. Lack of Immunoglobulins means you do not have the resources to fight off infections. If you get sick frequently, Immunoglobulins (IgG, IgM, IgA, IgE) should be tested to determine if deficiency is the cause, so that treatment can be administered before the immune system is further depleted. My post below has details and links about it.

graves60 profile image
graves60

Not sure but would like to find out! I have graves since 1994 had RAI I. 1997 been on levothyroxine but still have the antibodies

Miffie profile image
Miffie

All scientific research and knowledge indicates that autoimmune conditions do not mean a compromised immune system. That comes with Aids, HIV and chemotherapy treatment.

It is personal choice to think oneself more vulnerable than others. I seem to fall into an official category but from reading forums online I see that many much younger folk are sure they are high risk. Indeed I have seen a post where one younger woman announced she would die is she was exposed to the virus.

I am taking the view that as I am under seventy, diabetic with a heart murmur, some slight left ventricle issues hypothyroidism and a couple of autoimmune conditions I am not the most vulnerable. I will be sensible as those who have conditions necessitating the flu vaccine annually have been advised to be. I have been called for the flu vaccine for some years now. At no time has it been linked to any autoimmune condition, hypothyroidism or oesophageal problems it is down to diabetes.

I have heard of patients with Graves / Hashi asking GPs to vaccinate , these conditions however do not come under the at risk banner.

Our choice in regard to our behaviour at this time is personal.

ShootingStars profile image
ShootingStars in reply to Miffie

Actually, all scientific research and knowledge indicates that there is amble literature showing that Hashimoto's and Graves are comorbid for Immunoglobulin Deficiencies. Immunoglobulin Deficiencies mean a compromised immune system. If you don't have enough immunoglobulins, then you can't fight off infections.

Diabetes and heart problems in the high risk category for Covid 19. You are vulnerable to the virus.

Miffie profile image
Miffie in reply to ShootingStars

I thought and had been Hashimoto’s and Graves were like most other autoimmune conditions not compromised immune conditions. I wonder why the Government and all medical staff think that it relates to those with HIV or Cancer patients on chemotherapy and similar regimes.

In my ignorance I was unaware that Hashi and Graves patients have much more aggressive treatment thanI realised. I therefore apologise for not appreciating that these two groups are in this situation.

Much of my research into hypothyroidism/ hyperthyroidism is limited to medical text books in University libraries some years ago.

I do appreciate that my health record indicates medical knowledge indicates I may develop a more severe case of Covid-19 than others. I choose not to think of myself as a victim. I prefer to count my blessings and behave in a sensible manner.

Now you have identified that Hashi and Graves patients fall within the previous quite small numbers of compromised immune system group the numbers are huge. I was very concerned about my friends who are going through chemo at present and one with lupus but not about my friend with Hashi. She has also been told she is not at risk due to Hashimoto’s. I shall have to pass on your comments to her. Again I have a huge sigh of relief that it is not all autoimmune conditions which lead to compromised immune systems.

ShootingStars profile image
ShootingStars in reply to Miffie

They do not. Immunoglobulin deficiency has nothing g to do with HIV or cancer or similar regimes, whatever that is. HIV is asexually transmitted virus and is completely un relayed to immunoglobulin deficiency, which is usually genetic in cause. Suppressed immune system caused by cancer medications is completely different.

“I wonder why the Government and all medical staff think that it relates to those with HIV or Cancer patients on chemotherapy and similar regimes.”

Every person has an immune system. Immunoglobulins are just one part of it.

ShootingStars profile image
ShootingStars in reply to Miffie

My dear Miffie. Being high risk for vivid-19 because you have medical conditions that are beyond your control is not being a victim. Playing a victim is not the same as circumstances you cannot Control. You cannot help that you have health issues, but you can help not get covid-19 by practicing all strict guidelines and restrictions for high risk people.

Miffie profile image
Miffie in reply to ShootingStars

When I used the term victim I meant I try to keep comments upbeat. I am looking at the current situation as a time for some people to take care. Snot here but elsewhere I have seen many young people commenting how dreadful a situation they are in including one young lady who said if she became infected she would die. I feel that taking a view one id destined to suffer the worst displays victim culture. A purely personal opinion.

ShootingStars profile image
ShootingStars in reply to Miffie

Not all Hashimoto’s and Graves patients are low on immunoglobulins. Other autoimmune diseases can also be comorbid to immunoglobulin deficiencies, or a person could have no autoimmune disease and have a compromised immune system. The main symptom in my original post is if someone suffers from frequent infections, they could be low on immunoglobulins. Frequent infections are an indicator that the immune system is not healthy. When a patient presents with frequent infections, and especially serious infections, immunoglobulins are the first place that is usually looked.

Georgie120 profile image
Georgie120

I also checked the British Thyroid site and it does say that 'we' as thyroid deficient are not in the 'at risk' category.

If thyroid is an auto-ammune problem then thyroid can be affected.

I will abide by the British Thyroidl site until further notice..however as this is an unknown virus i will take precautions. Take care everyone use your own judgement xx

ShootingStars profile image
ShootingStars in reply to Georgie120

If someone has Hashimoto's or Graves, get frequent infections which is often caused by an Immunoglobulin Deficiency, then they are high risk. Lack or deficiency of Immunoglobulins means immunosuppressed. Immunoglobulins are what fight off infections. If you don't have enough immunoglobulins, then any virus, bacteria, or other pathogen is difficult to fight off.

revkrow profile image
revkrow

Thank you for all your responses. It's good to know that we can post concerns and questions even when the response is varied. I've found it helpful reading through them. I do feel a bit nervous about going back to work next week after being unwell as I would like just to take a bit more time to get completely better. Take good care everyone.

MjM2015 profile image
MjM2015

No you shall be ok.bunless you have any underlying issues ie Type1 Diabetes, MS, COPD Heart and lung problems.

Apparently, not in itself according to the BTF. But if you know you always get every cold and flu that goes round, then you personally might be more at risk.

Miffie profile image
Miffie in reply to Angel_of_the_North

Surely people who have flu regularly will have been put forward for flu vaccine by GP. I find it hard to believe that hospitals do not include a recommendation on discharge for vaccination in future years. Flu can and does kill people every year. If it is you who is in this situation I recommend you contact GP and ask why you are not in the vaccine call up . Take care

Angel_of_the_North profile image
Angel_of_the_North in reply to Miffie

Not so, only if you have certain conditions or are elderly - plus there was a study that showed that having a seasonal flu jab made you more susceptible to other viruses (like coronoviruses) that it didn't cover. I used to get summoned when I was getting asthma meds from GP, when I started buying my own (as I couldn't get a GP appt I could attend) I just dropped off the radar. Not that I ever had one a) in the days when they did allergy testing, I was always allergic to flu jab b) it is either cultured in eggs or caterpillars and I'm vegan, so not for me.

Miffie profile image
Miffie in reply to Angel_of_the_North

I can only offer you my deepest sympathies. I wonder what my vegan friends do. One has ha a flu vaccine every year for some time now. She is the carer of a thirty year old with severe autism, he too is vaccinated.

You have my sympathy that you find yourself hospitalised so often. What about pneumonia? Were you able to have that vaccine? Take care.

Angel_of_the_North profile image
Angel_of_the_North in reply to Miffie

I haven't been in hospital since 1974. There was no pneumonia vaccine 1975 as far as I know, certainly I was not offered one and wasn't put in hospital after diagnosis - I just thought it was a chest infection or my asthma getting worse. I can't even remember what was done - steroids, possibly anti-biotics and bed rest I think. We were a lot tougher in those days

Lisajane7 profile image
Lisajane7

I am reading so many conflicting advice. I think it should be assessed on an individual basis. Since I was diagnosed with Grave's in 2010, my health has declined rapidly and I now have a number of other conditions. I also pick up and get more unwell from common illness. If I have an infection I often require antibiotics and sometimes more than 1 course. It takes me longer to recover.

Also over the last 10 years my blood results have high lighted high white cells, neutrophils, lymphocytes and CRP. Also on and off low HB, low ferritin. I saw a Haemotologist a few years ago and they couldn't give me an answer as to why... but what I know from training is that basically your white cells increase to fight infection or disease and this then leaves a memory for future infections.

If this is a new illness, virus or bacterial then you won't have that memory immunity and your body has to work harder to fight it. We all know when we are unwell you feel increasingly tired, this is because the inflammitory responce needed to develop antibodies to attack what ever is invading the body is hard work! So I have this going on everyday!!! My body thinks it is fighting illness every day! So when it comes to getting a real threat, my body is already tired and under pressure and this is why I get so unwell and Im at higher risk of catching something

This makes me very vunerable to this virus!

I am being very cautious due to this reason.

Another reason is, every year my Gp sends for me to have the flu vaccine. If I wasn,t at higher risk they wouldn't do this.

I think we need to listen to our own bodies and make an informed decision based on our health.

Lets take care of ourselves so we can take care of others!

ShootingStars profile image
ShootingStars in reply to Lisajane7

You might not have enough immunoglobulins. People with Hashimoto's and Graves who get frequent infections are often found to have insufficient immunoglobins and cannot fight off infections. Specifically Common Variable Immunoglobulin Deficiency or Selective IgM Deficiency.

QandA profile image
QandA

Does anyone know if having hashi's entitles you to a free flu vaccine? I got an invite last time, but I think it was in error, unless you get it with hypothyroidism? Just wondering, as the way they described the "vulnerable" group today was people who were entitled to a free flu vaccine.

StitchFairy profile image
StitchFairy in reply to QandA

As well as certain conditions (not thyroid conditions), flu vaccine is also based on age in the UK. See here nhs.uk/conditions/vaccinati...

RockyPath profile image
RockyPath

Here is what an infectious disease specialist in the US has to say about why an autoimmune condition would make you more vulnerable to a dire outcome -- the robust immune response opens the lungs to secondary infection. "In some more-severe coronavirus infections, the body’s effort to heal itself may be too robust, leading to the destruction of not just virus-infected cells, but healthy tissue. Damage to the epithelium lining the trachea and bronchi can result in the loss of protective mucus-producing cells as well as the tiny hairs, or cilia, that sweep dirt and respiratory secretions out of the lungs."

The full text from Bloomberg is below:

"Infection generally starts in the nose. Once inside the body, the coronavirus invades the epithelial cells that line and protect the respiratory tract, said Taubenberger, who heads the viral pathogenesis and evolution section of the National Institute of Allergy and Infectious Diseases in Bethesda, Maryland. If it’s contained in the upper airway, it usually results in a less severe disease.

But if the virus treks down the windpipe to the peripheral branches of the respiratory tree and lung tissue, it can trigger a more severe phase of the disease. That’s due to the pneumonia-causing damage inflicted directly by the virus plus secondary damage caused by the body’s immune response to the infection.

“Your body is immediately trying to repair the damage in the lung as soon as it’s happening,” Taubenberger said. Various white blood cells that consume pathogens and help heal damaged tissue act as first-responders. “Normally, if this goes well, you can clear up your infection in just a few days.”

In some more-severe coronavirus infections, the body’s effort to heal itself may be too robust, leading to the destruction of not just virus-infected cells, but healthy tissue, Taubenberger said. Damage to the epithelium lining the trachea and bronchi can result in the loss of protective mucus-producing cells as well as the tiny hairs, or cilia, that sweep dirt and respiratory secretions out of the lungs.

“You have no ability to keep stuff out of the lower respiratory tract,” Taubenberger said. As a result, the lungs are vulnerable to an invasive secondary bacterial infection. Potential culprits include the germs normally harbored in the nose and throat, and the antibiotic-resistant bacteria that thrive in hospitals, especially the moist environments of mechanical ventilators."

bloomberg.com/news/articles...

I know for a while Boris was thinking Herd Immunity was a good solution for the UK. Everybody get sick who can survive and get well. But once the Imperial College of London released its projection of 510,000 deaths, Johnson changed his mind.

Newmummy82 profile image
Newmummy82

I’ve been taking timeric every day, it’s great for reducing inflammation and modulating the immune system to stop it over reacting to infections.

Newmummy82 profile image
Newmummy82 in reply to Newmummy82

Turmeric!

Lisajane7 profile image
Lisajane7 in reply to Newmummy82

I have tried Tumeric but it made me sick. 😞

ShootingStars profile image
ShootingStars

YES, absolutely YES, if you get infections and also have an immunoglobulin deficiency*, this means your immune system is compromised. (note that Hashimoto's is listed below under IgM Deficiency, SIgMD.). Immunoglobulins are the antibodies that fight off viruses, bacteria, and other pathogens, and if you do not have enough of them, infections occur more frequently and are more difficult to fight off. Hashimoto's and other autoimmune diseases are comorbid to several immunoglobulin deficiencies. Selective IgM Deficiency (SIgMD) is the immunoglobulin deficiency that is found in people with Hashimoto's. Common Variable Immunodeficiency (CVID) is also found in people with Hashimoto's and also other autoimmune diseases.

*If you get a lot of infections, it's important to know if you have an Immunoglobulin Deficiency so that you can receive the proper treatment so that you do not further deplete your immune system. Your doctor can test your Immunoglobulin G, Immunoglobulin M, Immunoglobulin A and Immunoglobulin E. Treatment might be as easy as prompt antibiotics or antifungal medication at the earliest onset of infection, or in some cases prophylactic antibiotics or antifungal medication.

Immunoglobulin M (IgM) is the "first responder" antibody that is first on the scene when a virus, bacteria or other pathogen appears. If you don't have enough, this is not good, and is considered Selective IgM Deficiency, SIgMD.

"People with secondary SIgMD usually have too little IgM, rather than none at all. For this reason, their symptoms of SIgMD usually are more mild and may go away if the associated underlying condition improves.[1] Conditions that have been reported in association with SIgMD include:[1]

Cancers such as multiple myeloma, clear cell sarcoma, and lymphocytic leukemias.

Blood disorders such as monoclonal gammopathies and immune thrombocytopenia.

Autoimmune diseases such as lupus, rheumatoid arthritis, celiac disease, Crohn's disease, and Hashimoto disease.

"

rarediseases.info.nih.gov/d...

Immunoglobulin G (IgG) is the most common antibody and is part of secondary immune response. 75% of immunoglobulins are IgG. It also fights off viruses, bacteria and other pathogens. If you are deficient in IgG, you have CVID.

Immunoglobulin A (IgA) is found on the exterior surface of mucous membranes and is secreted into tears, saliva, mucous.

Immunoglobulin E (IgE) is found in the least quantity in comparison to the others. It's found in the respiratory and GI tracts and defends the body against parasites and is responsible for allergic reactions.

The original and readable table can be found here in this document in the tables at the bottom of the page, second from the left: ncbi.nlm.nih.gov/pmc/articl...

Table 2

Autoimmune conditions in 432 adult CVID/IgGSD index patients1.

Condition(s)CVID (n = 34)IgGSD (n = 398)Value of P

Sjögren's syndrome, % (n) 20.6 (7) 6.5 (26)0.0031

Hashimoto's thyroiditis, % (n)2 11.8 (4) 2.8 (11)0.0059

Rheumatoid arthritis, % (n) 11.8 (4) 5.3 (21)0.1199

Gastrointestinal tract, % (n)32.9 (1)2.3 (9)0.5634

Multiple sclerosis, % (n) 2.9 (1) 0.3 (1)0.1514

Positive ANA, % (n)4 2.9 (1) 3.5 (14)0.6664

Psoriatic arthritis, % (n)2.9 (1)1.3 (5)0.3903

Autoimmune hearing loss, % (n)00.3 (1)0.9213

Autoimmune hemolytic anemia, % (n)501.0 (4)0.7196

Diabetes mellitus, type 1, % (n)01.3 (5)0.6624

Graves' disease, % (n)00.5 (2)0.7820

kalel profile image
kalel

Hey I am pretty sure my immune system must be compromised, I have had RA for years but I have been weaned off the meds, apart from once a month jabs and knowing I have thyroid problems, lol as much as I feel fit and healthy within myself. I don't think we can ever know what type of affects we have in the long run to being on meds etc, can we? I have been following a lot of functional health drs about how we can help ourselves but the info is over welming as well, cause there is so much out there. Unless anyone has other suggestions for now I am at home most of the time, in self isolation. Not ideal because I am supposed to go out to work but not sure if I had other options. Until my mother stops working next week and she knows she is virus free and other people in my life. Thought it was for the best I stay well clear. I am buying an N9 ventilation mask, I know some are like don't wear them but I would rather be safe. I have personally realised I don't want to panic or live in fear because that is also lowering our immune system so am I am just getting on with things now, not much else we can do, is there? Stay safe guys, take good care guys. :))

sy28 profile image
sy28

yes ... I would self isolate as a precaution

LynneG profile image
LynneG

Why are we in the vulnerable at risk category of this Corona Virus with autoimmune inc Hashimotos

I think it maybe that with autoimmune, the immune system is overreacting/confused/overwhelmed however you want to look at it but basically the immune system is attacking own cells. Sometimes the attack can calm down but then something makes it flare. Illness, infections, menopause, stress, whatever. Which could be stress to the body caused by vaccination which is why I have never had the flu jab.

But I read that the way this coronus virus kills is it triggers the immune system into overdrive/overreact. (well we are already in that position) and in the worst case scenario its the inflammation driven out of control caused by the reaction of the immune system that causes massive organ failure as with sepsis, when you may not survive.

Also I watched a very good explanitive video which showed how the virus affects the lungs. It doesn't act like other infections which is why it is so dangerous. The immune system is triggered to create inflammation as is how it heals the cells but this virus creates an ongoing inflammatory condition in spiralling inflammation into overdrive,

The cell walls of the airsacs in the lungs have to be really thin so that the oxygen breathed in will diffuse readily into the blood stream. The inflammation causes

a) causes the cell walls of the air sacs to thicken (so prohibited diffusion of oxygen - if at all)

b) causes interstitial fluid (fluid between cells) to leak into the air sacs and makes them collapse, hence difficutly breathing/getting oxygen

So I believe this will be why the number 1 risk is listed as heart disease, as puts so much pressure on the heart re lack of oxygen also high BP and Diabetes which is an inflammatory disease as in uncontrolled inflammation caused by blood sugar abnormality.

Stands to reason to me that anyone with an abnormal inflammatory response as in autoimmune is in the vulnerable at risk category

kalel profile image
kalel

I would just be careful, like if you have to go out, find a mask, which are hard to do because unfortunately the government screwed up things, well in my opinion and people are now selling masks online for a stupid amount. For now I am personally prepared to self isolate, think the hardest issue will be for many is the shortage of food in the stores, especially the older generation, can't even get food online for a good few weeks, I know food is prob the least of the concerns though. The issue with the virus now is , not the same as it first started spreading so now, as sad as it is to say, they are getting serious side effects. Hopefully everyone can work together to flatten the curve, stay safe guys.

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